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Quality of Life in Obese Patients from a Multidisciplinary Bariatric Consultati...

Rego de Figueiredo, I; Carvalho Vasques, M; Cunha, N; Martins, D; Silva-Nunes, J

Obesity is a chronic disease defined by a body mass index of ≥30 kg/m2, which can result in a decrease in quality of life (QoL). Our study aim was to assess the QoL of an obese population of bariatric surgery (BS) candidates, and to compare it to both that of a non-bariatric obese population (C) and that of the general population. This was a cross-sectional study using: (1) the EQ-5D-3L instrument: comparing BS...


Adaptive Filtering for the Maternal Respiration Signal Attenuation in the Uteri...

Martins, D; Batista, A; Mouriño, H; Russo, S; Esgalhado, F; dos Reis, C; Serrano, F; Ortigueira, M

The electrohysterogram (EHG) is the uterine muscle electromyogram recorded at the abdominal surface of pregnant or non-pregnant woman. The maternal respiration electromyographic signal (MR-EMG) is one of the most relevant interferences present in an EHG. Alvarez (Alv) waves are components of the EHG that have been indicated as having the potential for preterm and term birth prediction. The MR-EMG component in t...


Dexamethasone Intravitreal Implant (Ozurdex) in Diabetic Macular Edema: Real-Wo...

Neves, P; Matias, I; Rodrigues, J; Santos, M; Dutra-Medeiros, M; Martins, D

Aim: To investigate the safety and efficacy of intravitreal dexamethasone implants (Ozurdex®/DEX) in patients with diabetic macular edema (DME) either naïve or non-naïve to anti-VEGF therapies who switched to DEX implant independent of response to anti-vascular endothelial growth factors (anti-VEGFs). Methods: This was an audit retrospective review of medical records of patients with DME who switched to the DEX...


Pericardial NT-Pro-BNP and GDF-15 as Biomarkers of Atrial Fibrillation and Atri...

Fragão-Marques, M; Barroso, I; Farinha, R; Miranda, IM; Martins, D; Mancio, J; Rocha-Neves, J; Guimarães, JT; Leite-Moreira, A; Falcão-Pires, I

Aims: This study aimed to evaluate the association of GDF-15 and NT-pro-BNP in two different biological matrices with AF in severe aortic stenosis patients undergoing aortic valve replacement surgery (AVR), its association with atrial matrix remodeling, as well as with 30-day postoperative outcomes. Main Methods: One hundred and twenty-six patients between 2009 and 2019 with severe aortic stenosis undergoing AV...


Cd44v6 high membranous expression is a predictive marker of therapy response in...

Almeida, GM; Pereira, C; Park, JH; Lemos, C; Campelos, S; Gullo, I; Martins, D; Gonçalves, G; Leitão, D; Neto, JL; André, A; Borges, C; Almeida, D

In gastric cancer (GC), biomarkers that define prognosis and predict treatment response remain scarce. We hypothesized that the extent of CD44v6 membranous tumor expression could predict prognosis and therapy response in GC patients. Two GC surgical cohorts, from Portugal and South Korea (n = 964), were characterized for the extension of CD44v6 membranous immuno-expression, clinicopathological features, patient...


The role of immunotherapy in advanced renal cell carcinoma

Mondlane, ER; Abreu-Mendes, P; Martins, D; Cruz, R; Mendes, F


Fine-needle aspiration cytology of axillary lymph node in patients with breast ...

Marques, Rita; Figueiredo, J P; Almeida, D; Martins, D; Sousa, V; Agapito, P

Introduction The breast is a glandular organ responsive to hormonal changes, therefore, according to the woman’s reproductive stage, the prevalence of different types of breast diseases varies. Breast cancer is the most prevalent (34,6%) in Portuguese women, its incidence has been rising and is most common in postmenopausal women (75%). However, younger women often present worst prognosis and more aggressive be...

Date: 2020   |   Origin: Citotech Online - Case Review


Fifteen years of coronary intravascular ultrasound in percutaneous coronary int...

Azevedo Guerreiro, R; Fernandes, R; Campante Teles, R; Canas da Silva, P; Pereira, H; Cruz Ferreira, R; Costa, M; Seixo, F; Farto E Abreu, P; Pipa, JL

INTRODUCTION: Coronary intravascular ultrasound (IVUS) is increasingly important in catheterization laboratories due to its positive prognostic impact. This study aims to characterize the use of IVUS in percutaneous coronary intervention (PCI) in Portugal. METHODS: A retrospective observational study was performed based on the Portuguese Registry on Interventional Cardiology of the Portuguese Society of Cardiol...

Date: 2020   |   Origin: Saúde - CUF

A dry and fully dispersible bacterial cellulose formulation as a stabilizer for...

Martins, D; Berta Nogueiro Estevinho; Fernando Rocha; Dourado, F; Gama, M

Bacterial cellulose (BC) is an emerging alternative to plant cellulose in different applications. Several works demonstrated the potential of never-dried BC; however, envisioning real industrial applications, a dry product retaining its functional properties upon rehydration is preferable. A dry and completely redispersible formulation of BC with carboxymethyl cellulose (CMC) was prepared by Spray-drying. The o...


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