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Protective Effect of cashew gum (Anacardium occidentale L.) on 5-Fluorouracil-i...

Miranda, João Antônio Leal de; Barreto, João Erivan Façanha; Martins, Dainesy Santos; Pimentel, Paulo Vitor de Souza; Costa, Deiziane Viana da Silva

Intestinal mucositis is a common complication associated with 5-fluorouracil (5-FU), a chemotherapeutic agent used for cancer treatment. Cashew gum (CG) has been reported as a potent anti-inflammatory agent. In the present study, we aimed to evaluate the e ect of CG extracted from the exudate of Anacardium occidentale L. on experimental intestinal mucositis induced by 5-FU. Swiss mice were randomly divided into...

Date: 2019   |   Origin: Oasisbr

Gastroprotective effects of sulphated polysaccharides from the Alga Caulerpa me...

Carneiro, José Gerardo; Holanda, Ticiana de Brito Lima; Quinderé, Ana Luíza Gomes; Frota, Annyta Fernandes; Soares, Vitória Virgínia Magalhães

The development of the gastric lesion is complex and the result of the imbalance between aggressive and protective factors, involving the generation of free radicals and disturbance in nitric oxide (NO) production. Sulphated polysaccharides (SP), from marine algae, are widely used in biotechnological and pharmaceutical areas. In this study, we evaluated the effects of SP from the green marine alga Caulerpa mexi...

Date: 2018   |   Origin: Oasisbr

Efeito da Cecropia pachystachya na inflamação e no estresse oxidativo na úlcera...

Martins, Dainesy Santos

Peptic ulcer (UP) is a gastrointestinal disease in which acute and chronic inflammation of the stomach occurs, as well as duodenum, which can lead to abdominal pain, nausea, vomiting and other symptoms. UP is multifactorial by Helicobacter pylori, use of non-steroidal anti-inflammatory drugs, alcohol, smoking and cancer treatment, resulting in an imbalance between the defensive and harmful factors. Cecropia pac...

Date: 2017   |   Origin: Oasisbr

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