Background: While ketamine (KET) has gained increasing scientific attention for its novel therapeutic applications, there has also been a parallel global rise in its non-medical, recreational use. [1]. Due to its effects on the central nervous system—such as dissociation, perceptual alterations, and its well-known anesthetic properties—KET is frequently used recreationally for its psychoactive effects. [2]. As ...
The increasing interest in utilizing psychedelics for therapeutic purposes demands the development of tools capable of efficiently monitoring and accurately identifying these substances, thereby supporting medical interventions. 4-Bromo-2,5-dimethoxyphenethylamine (2C-B) has gained significant popularity as one of the most widely used psychedelic compounds in non-medical settings. In this study, we aimed to cre...
The following article focuses on the development of a visual exploratory study in the form of a diagnostic, tested in a learning experience to support the development of the final project. A project developed in the field of visual communication design, degree of Visual Communication Design and Audiovisual Production of the School of Applied Arts, Castelo Branco Polytechnic Institute, Portugal. The visual diagn...
Introduction: Valve surgery through a median sternotomy has been the standard approach, but in the past decade various minimally invasive procedures have gained increasing traction among physicians and patients. Materials and Methods: We present a series of three patients submitted to minimally invasive combined aortic and mitral valve surgery, performed through right lateral thoracotomy. Results: We report no ...
Background: Oxytocin (OXT) has attracted research interest for its potential involvement in many of the behavioural problems observed in childhood. Due to its logistical advantages, saliva is an attractive fluid to quantify neuropeptides in children. Salivary OXT has been suggested as a potential biomarker for psychopathology during childhood. However, several questions still remain about the extent to which, a...
Introduction: Involvement of the ascending/aortic arch in the thoracic aorta pathology can preclude thoracic endovas- cular aortic repair (TEVAR) due to the absence of an adequate proximal landing zone. Hybrid interventions combining ascending/aortic arch replacement with TEVAR of the descending thoracic aorta (DTA) are associated with good outcomes. Despite the existence of dedicated devices (E-vita®, Thorafle...
This paper focuses on analyzing and designing the control system in a DC microgrid, which is responsible to provide energy for a robotic system built to inspect distribution power lines. The microgrid was projected to feed sensors, microcontrollers, and a DC motor. Also, in order to provide energy for the system, lithium-ion batteries and photovoltaic cells are employed as sources of the microgrid. With this ar...
The present study focuses on investigating the aerodynamic interaction between a three-element wing and wheel in ground effect, following the Formula One regulation change set for 2022, among which is the simplification of the front wing. This was accomplished by conducting a three-dimensional computational fluid dynamics analysis, using a Detached-Eddy Simulation approach, on a simplified one-quarter model of ...