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Cultural Translation and Validation of the Bariatric Quality of Life Index to E...

Rego de Figueiredo, Inês; Vasques de Carvalho, Miguel; Cunha, Nelson; Martins, Diana; Silva-Nunes, José

Introduction: Obesity is a chronic noncommunicable disease, defined by a body mass index over 30 kg/m2. Its impact is not restricted to its association with higher risks of mortality and morbidity from other noncommunicable diseases, but also with a decrease in quality of life (QoL). There are several tools to assess QoL, from generic health-related tools to obesity-related specific ones. However, to assess QoL...

Date: 2024   |   Origin: Acta Médica Portuguesa

Changes in Vessel Traffic Disrupt Tidal Flats and Saltmarshes in the Tagus Estu...

Martins, Diana; Alves da Silva, Andreia; Duarte, João; Canário, João; Vieira, Gonçalo

The Tagus Estuary is one of the largest in Europe with 320 km2 , and it has been, for centuries, a gateway to Lisbon. This study focuses on the Moita-Montijo Bay and on the recent dynamics of its tidal flats and saltmarshes. Aerial photographs, orthomosaics, and very high-resolution satellite imagery were used to analyze landcover and shoreline changes. Tidal flats have shown expansion from 1977 to 1995, but si...


The historical learning for a culture of democracy, coexistence and cooperation

Ribeiro, Cláudia Pinto; Alves, Luis Alberto Marques; Vieira, Helena; Moreira, Ana Isabel; Martins, Diana; Magalhães, Daniela; Lopes, Lara


The role of immune checkpoint blockade in acute myeloid leukemia

Silva, Margarida; Martins, Diana; Mendes, Fernando

Immune checkpoint inhibition (ICI) has emerged as a therapeutic option for acute myeloid leukemia (AML) for patients that suffer from relapsed or high-risk disease, or patients ineligible for standard therapy. We aimed to study ICI as monotherapy and/or combined therapy (with chemotherapy (QT), for AML patients. The PRISMA statement was used. The literature used comprised clinical trials, randomized controlled ...


Quality of life in obese patients from a multidisciplinary bariatric consultati...

Figueiredo, Inês Rego de; Vasques, Miguel Carvalho; Cunha, Nelson; Martins, Diana; Silva-Nunes, José

Obesity is a chronic disease defined by a body mass index of ≥30 kg/m2, which can result in a decrease in quality of life (QoL). Our study aim was to assess the QoL of an obese population of bariatric surgery (BS) candidates and to compare it to both that of a non-bariatric obese population (C) and that of the general population. This was a cross-sectional study using: (1) the EQ-5D-3L instrument: comparing BS ...


Cross-cultural translation and validation to Portuguese of the bariatric qualit...

Figueiredo, Inês Rego de; Carvalho, Miguel Vasques; Cunha, Nelson; Martins, Diana; Silva-Nunes, José

Introduction: Obesity is a chronic noncommunicable disease, defined by the body mass index (BMI) ≥ 30Kg/m2. Its burden is not restricted to mortality and morbidity from other noncommunicable diseases, but also from a decrease in quality of life (QoL). There are several tools for assessing QoL, from generic health-related tools to obesity-related tools. However, to assess QoL in patients undergoing bariatric sur...


Psychopathological and quality of life gender differences in obese patients who...

Figueiredo, Inês Rego de; Carvalho, Miguel Vasques; Cunha, Nelson; Martins, Diana; Silva-Nunes, José

Introduction: Gender differences in obesity go from prevalence, access to treatment, baseline characteristics, outcomes, and complications. Our aim was to access baseline differences in a bariatric surgery cohort, with an emphasis on psychopathology and quality of life (QoL). Methodology: Cross-sectional study at a bariatric surgery clinic performed by application of psychological (Y-BOCS, HAD scale, FCQ-S/T, B...


Under a cloak of terror: violence and armed conflict in Europe

Ribeiro, Cláudia Pinto; Alves, Luís Alberto Marques; Vieira, Helena; Moreira, Ana Isabel; Martins, Diana; Magalhães, Daniela; Lopes, Lara

As it is impossible to prove that human nature is intrinsically violent and warlike, history does not allow us to deny that war is one of the most present elements at different times. As an omnipresent phenomenon, it can also be considered a total social fact due to the multiple implications it entails. Furthermore, due to its implications, it becomes an object of historical study that is interpreted in differe...


Increasing the resistance of Mediterranean extensive green roofs by using nativ...

Esfahani, Razieh; Paço, Teresa; Martins, Diana; Arsénio, Pedro

While the use of extensive green roofs (EGRs) is increasing worldwide, Mediterranean conditions complicate EGR design due to their long, dry summers with intense solar radiation. Aim: To inform sustainable EGR design for Mediterranean regions, we explored the use of resilient, droughttolerant species in experimental EGRs. Methods: We selected four native species that are known to spontaneously establish themsel...

Date: 2022   |   Origin: Repositório da UTL

Upregulation of tRNA-Ser-AGA-2-1 promotes malignant behavior in normal bronchia...

Santos, Mafalda; Fidalgo, Ana; Varanda, Ana Sofia; Soares, Ana Raquel; Almeida, Gabriela M.; Martins, Diana; Mendes, Nuno; Oliveira, Carla

Serine tRNAs (tRNASer) are frequently overexpressed in tumors and associated with poor prognosis and increased risk of recurrence in breast cancer. Impairment of tRNA biogenesis and abundance also impacts proteome homeostasis, and activates protein quality control systems. Herein, we aimed at testing whether increasing tRNASer abundance could foster tumor establishment through activation of the UPR. In order to...


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