14 documents found, page 1 of 2

A giant hybrid organic-inorganic octahedron from a narrow rim carboxylate calix...

A simple alternative to prodrug: the hydrochloride salt monohydrate of the pros...

Synthesis, characterization, and structural determination of copper(II) complex...

Four mononuclear copper(II) complexes, [Cu(LFQM-115)2] (1), [Cu(LFQM-116)2] (2), [Cu(LFQM-117)2] (3) and [Cu(octyloxy)2] (4) [LFQM-115 = 2-hydroxy-4-O-methylbenzophenone (C14H11O3), LFQM-116 = 2-hydroxy-4-O-butylbenzophenone (C17H18O3), LFQM-117 = 2-hydroxy-4-O-(33-dimethylallyl)benzophenone (C18H18O3) and octyloxy = 2-hydroxy-4-O-octylbenzophenone (C21H25O3)], have been prepared and investigated by infrared sp...

A novel platinum complex containing a piplartine derivative exhibits enhanced c...

Piplartine (piperlongumine) is a plant-derived compound found in some Piper species that became a novel potential antineoplastic agent. In the present study, we synthesized a novel platinum complex containing a piplartine derivative cis-[PtCl(PIP-OH)(PPh3)2]PF6 (where, PIP-OH = piplartine demethylated derivative; and PPh3 = triphenylphosphine) with enhanced cytotoxicity in different cancer cells, and investigat...

A comparative study on the crystal structure of bicycle analogues to the natura...

Herein we described structural insights of a series of analogues to helminthosporin phytotoxins. The key reaction used to prepare the compounds corresponded to the [3 + 4] cycloaddition between the oxyallyl cation generated from 2,4-dibromopentan-3-one and different furans. Their structures were confirmed upon IR, NMR and X-ray diffraction analyses. While bicycles 7, 8 and 9 crystallize in the centrosymmetric m...

Calix[n]arene-catalyzed three-component povarov reaction: microwave-assisted sy...

A new one-pot cascade reaction-based application of Povarov reactions with a p-sulfonic acid calix[4]arene catalyst for the synthesis of a series of 34 julolidine derivatives with substituents at C8 or C9 in good to excellent yields is reported. These microwave-assisted reactions proceeded efficiently, had short reaction times, were metal-free, were low cost, and used an inexpensive, easily available and nontox...

Conformerism, enantiomorphism and double catemer motifs in para-substituted nos...

We have here elucidated the crystal structures of five nostoclide analogues. A common feature in all compounds is a substituent at the para-position of the benzylidene group. Compounds with either bromine (3) or hydroxyl (4) as para-substituent crystallizes with Z’ = 2 as result of conformerism. It was also observed that Z' > 1 in the compound with a para-dimethylamino substituent (1). However, its four crystal...

Chemical variation in the essential oil of Hyptis suaveolens (L.) Poit., under ...

This study was performed to establish the correlation between the growth conditions and essential oil composition of Hyptis suaveolens from Alfenas (MG), Brazil. The plants were grown in a greenhouse, four treatments were used and they were harvested at two different periods of time (60 and 135-day-old plants). The essential oil composition was determined by GC-MS analysis. The terpenes spathulenol, globulol, d...

Conformational variability in sulfonamide chalcone hybrids : crystal structure ...

Four sulfonamide-chalcone derivatives were prepared and their crystal structure were elucidated by single-crystal X-ray diffraction technique. They were synthesized by Claisen-Schmidt condensation reaction between N -(4-acetylphenyl)benzenesulfonamide or N -(4-acetylphenyl)- 2,5-dichlorobenzenesulfonamide with benzaldehyde or p -nitrobenzaldehyde. Values of Z’ > 1 are found in three compounds as a consequence o...

Conformerism, enantiomorphism and double catemer motifs in para-substituted nos...

We have here elucidated the crystal structures of five nostoclide analogues. A common feature in all compounds is a substituent at the para-position of the benzylidene group. Compounds with either bromine (3) or hydroxyl (4) as para-substituent crystallizes with Z’ ¼ 2 as result of conformerism. It was also observed that Z' > 1 in the compound with a para-dimethylamino substituent (1). However, its four crystal...