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Gestão das cefaleias em Portugal: consenso das Sociedades Portuguesas de cefale...

Gil-Gouveia, Raquel; Parreira, Elsa; Martins, Isabel Pavão; Luzeiro, Isabel; Pereira, Raúl Marques; Plácido, Madalena; Palavra, Filipe

As cefaleias são uma causa significativa de incapacidade a nível global, com a enxaqueca a ocupar o segundo lugar entre as doenças com mais anos vividos com incapacidade. A maioria dos doentes com cefaleias, incluindo enxaqueca, podem e devem ser diagnosticados, tratados e acompanhados eficazmente nos cuidados de saúde primários. Isso não só reduz a incapacidade associada a estas patologias, mas também previne ...


Uncovering longitudinal changes in the brain functional connectome along the mi...

Esteves, Inês; Fouto, Ana R.; Ruiz-Tagle, Amparo; Caetano, Gina; Nunes, Rita G.; Silva, Nuno A. da; Vilela, Pedro; Martins, Isabel Pavão

Changes in large-scale brain networks have been reported in migraine patients, but it remains unclear how these manifest in the various phases of the migraine cycle. Case-control fMRI studies spanning the entire migraine cycle are lacking, precluding a complete assessment of brain functional connectivity in migraine. Such studies are essential for understanding the inherent changes in the brain of migraine pati...


Uncovering longitudinal changes in the brain functional connectome along the mi...

Esteves, Inês; Fouto, Ana R.; Ruiz-Tagle, Amparo; Caetano, Gina; Nunes, Rita G.; da Silva, Nuno A.; Vilela, Pedro; Martins, Isabel Pavão

Background: Changes in large-scale brain networks have been reported in migraine patients, but it remains unclear how these manifest in the various phases of the migraine cycle. Case-control fMRI studies spanning the entire migraine cycle are lacking, precluding a complete assessment of brain functional connectivity in migraine. Such studies are essential for understanding the inherent changes in the brain of m...


Working memory during spontaneous migraine attacks: an fMRI study

Ruiz-Tagle, A.; Figueiredo, Patrícia; Pinto, Joana; Vilela, Pedro; Martins, Isabel Pavão; Gil-Gouveia, Raquel

Objective: To investigate the neural correlates of working memory during a spontaneous migraine attack compared to the interictal phase, using functional magnetic resonance imaging (fMRI). Background: Cognitive disturbances are commonly observed during migraine attacks, particularly in the headache phase. However, the neural basis of these changes remains unknown. Methods: In a fMRI within-subject test-retest d...


Recurrent syncope during migraine attacks

Dias Da Costa, Mariana; Nunes Vicente, Beatriz; Dourado Sotero, Filipa; Martins, Isabel Pavão

Migraine is a cyclic condition with attacks consisting mainly of intense headaches, sensory intolerance, and nausea or vomiting. Loss of consciousness during attacks is often attributed exclusively to a neurally mediated reflex to pain, although it may also be due to migraine's autonomic impairment, with cardiac conduction abnormalities, probably in relation to a degree of reduced sympathetic function. We repor...


Locations of objects are better remembered than their identities in naturalisti...

Coco, Moreno I.; Maruta, Carolina; Martins, Isabel Pavão; Sala, Sergio Della

Objective: Retaining the identity or location of decontextualized objects in visual short-term working memory (VWM) is impaired by healthy and pathological ageing, but research remains inconclusive on whether these two features are equally impacted by it. Moreover, it is unclear whether similar impairments would manifest in naturalistic visual contexts. Method: 30 people with mild cognitive impairment (MCI) and...


Cranial autonomic symptoms and neck pain in differential diagnosis of migraine

Vicente, Beatriz Nunes; Oliveira, Renato; Martins, Isabel Pavão; Gil-Gouveia, Raquel

Cranial autonomic symptoms and neck pain have been reported to be highly prevalent in migraine, although they are rarely considered in clinical evaluation. The aim of this review is to focus on the prevalence, pathophysiology, and clinical characteristics of these two symptoms, and their importance in the differential diagnosis between migraines and other headaches. The most common cranial autonomic symptoms ar...


Altered functional connectivity in a sensorimotor-insular network during sponta...

Araújo, Raquel Pestana; Figueiredo, Patricia; Pinto, Joana; Vilela, Pedro; Martins, Isabel Pavão; Gil-Gouveia, Raquel

Background: Previous functional magnetic resonance imaging studies have identified brain-connectivity alterations across multiple regions in people with migraine when compared to healthy controls. Few studies have focused on such changes throughout the different phases of the migraine cycle. We aimed to investigate functional connectivity during spontaneous occurring episodic migraine attacks, in comparison to ...


Profile of cognitive impairment in late-stage Parkinson's disease

Sousa, Catarina Severiano e; Fabbri, Margherita; Godinho, Catarina; Simões, Rita Moiron; Chendo, Inês; Coelho, Miguel; Martins, Isabel Pavão

Introduction: The profile of cognitive impairment associated with the late stages of Parkinson's disease (LSPD) is rarely reported. Its characterization is necessary to better understand the cognitive changes that occur as the disease progresses and to better contribute to its management.


Clinical presentation and neural correlates of stroke‐associated spatial delusions

Alves, Pedro Nascimento; Fonseca, Ana Catarina; Melo, Teresa Pinho e; Martins, Isabel Pavão

Background and purpose: Incongruent beliefs about self-localization in space markedly disturb patients' behavior. Spatial delusions, or reduplicative paramnesias, are characterized by a firm conviction of place reduplication, transformation, or mislocation. Evidence suggests they are frequent after right hemisphere lesions, but comprehensive information about their clinical features is lacking. Methods: We pros...


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