6 documents found, page 1 of 1
Diazepam influences urinary bioindicator of occupational toluene exposure
Silveira, Alberto Thalison; Albuquerque, Ana Carolina Campos; Lepera, Jose Salvador [UNESP]; Martins, IsaritaMade available in DSpace on 2018-11-26T17:15:26Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG); In the present study, we investigated the influence of diazepam (DZP) on the excretion of TOL by examining their urinary metabolites, hippuric acid (HA) and ortho-creso...
Study of the correlation between blood cholinesterases activity, urinary dialky...
Santos, Mariane Gonçalves; Vitor, Ricardo Vilela; Nakamura, Maurício Gustavo; Morelini, Luana de Souza; Ferreira, Rafaela ScalcoOs organofosforados (OPs) são amplamente usados como praguicidas e a atividade da colinesterase sanguínea bem como os metabólitos urinários desses praguicidas têm sido reportados como biomarcadores eficazes para avaliar casos de exposição. Além disso, os OPs podem induzir mutagênese e o teste de micronúcleo de medula óssea é uma boa alternativa para avaliar os danos cromossômicos. Esse artigo reporta um estudo ...
QuEChERS-HPLC-DAD method for sulphonamides in chicken breast
Machado, Simone Caetani; Landin-Silva, Mariane; Maia, Patrícia Penido; Rath, Susanne; Martins, IsaritaO desenvolvimento de um método QuEChERS-HPLC-DAD usando uma coluna Lichrospher RP-60 Select B (250 x 4,6 mm x 5 µm) a 40 ºC, fase móvel constituída por tampão de fosfato: acetonitrila (75:25, v/v) a uma vazão inicial de 0,5 mL min-1, aumentando 1,2 mL min-1 e a 265 nm é apresentado para a determinação simultânea de sulfadiazina, sulfametoxipiridazina e sulfametoxazol em amostras de peito de frango. O QuEChERS é...
Liquid-liquid extraction combined with high performance liquid chromatography-d...
Sanson, Ananda Lima; Silva, Suéllen Cristina Rennó; Martins, Matheus Coutinho Gonçalves; Giusti-Paiva, Alexandre; Maia, Patrícia PenidoA liquid-liquid extraction (LLE) combined with high-performance liquid chromatography-diode array detection method for simultaneous analysis of four chemically and structurally different antineoplastic drugs (cyclophosphamide, doxorubicin, 5-fluorouracil and ifosfamide) was developed. The assay was performed by isocratic elution, with a C18 column (5 µm, 250 x 4.6 mm) and mobile phase constituted by water pH 4....
Simultaneous detection of three antineoplastic drugs on gloves by liquid chroma...
Alcântara, Adélia Maria Pimenta de Pádua; Vitor, Ricardo Vilela; Vieira, Elisabeth Pizzamiglio; Martins, IsaritaThe aim of this study was to develop a method for simultaneous detection of antineoplastic drugs on gloves since, in occupational exposure, the main contamination route is through dermal contact, which may occur via prolonged contact with contaminated surfaces or materials. The assay was performed by liquid chromatography using the following conditions for the detection of 5-fluorouracil (5-FU), methotrexate (M...
Single gas chromatography method with nitrogen phosphorus detector for urinary ...
Malafatti, Lusiane; Maia, Patrícia Penido; Martins, Matheus Coutinho Gonçalves; Siqueira, Maria Elisa Pereira Bastos de; Martins, IsaritaNicotine is a major addictive compound in cigarettes and is rapidly and extensively metabolized to several metabolites in humans, including urinary cotinine, considered a biomarker due to its high concentration compared to other metabolites. The aim of this study was to develop a single method for determination of urinary cotinine, in active and passive smokers, by gas chromatography with a nitrogen phosphorus ...