2 documents found, page 1 of 1
X-chromosomal STRs: Metapopulations and mutation rates
Gusmão, L.; Antão-Sousa, S.; Faustino, M.; Abovich, M.A.; Aguirre, D.; Alghafri, R.; Alves, C.; Amorim, A.; Arévalo, C.; Baldassarri, L.The analysis of STRs located on the X chromosome has been one of the strategies used to address complex kinship cases. Its usefulness is, however, limited by the low availability of population haplotype frequency data and lack of knowledge on the probability of mutations. Due to the large amount of data required to obtain reliable estimates, it is important to investigate the possibility of grouping data from p...
Results of the GEP-ISFG collaborative study on an X-STR Decaplex
Gusmão, L.; Alves, C.; Sánchez-Diz, P.; Zarrabeitia, M.T.; Abovich, M.A.; Aragón, I.; Arce, B.; Arrieta, G.; Arroyo, E.; Atmetlla, I.; Baeza, C.A collaborative work was carried out by the Spanish and Portuguese ISFG Working Group with a PCR multiplex for X chromosome STRs. Markers were selected among those described as polymorphic in humans and that have been used by some laboratories in forensics. Primers and various technical methods were investigated with the aim of optimizing a multiplex for the 10 selected X-STRs. Primer mix stock solutions were s...