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The Alien Neurology

Prevalence of high-grade endometrioid endometrial cancer of no specific molecul...

BACKGROUND: Endometrial cancer of no specific molecular profile (NSMP) represents the most prevalent molecular subtype of endometrial cancer, comprising over 50 % of all diagnoses. Although studies have explored the prevalence of the NSMP subtype, to our knowledge, no systematic review or meta-analysis has specifically targeted grade 3 (G3, high-grade) tumors. OBJECTIVES: We aimed to determine the prevalence of...

Global power sharing and virtual inertia control for the interlinking modular u...

Hybrid ac/dc microgrids (HMGs) have gained significant attention in recent years for their efficient integration of distributed energy resources and their capability to operate independently from the grid during islanded mode. The bidirectional interlinking converter (BIC) is the key element that coordinates power exchange between sub-grids to achieve precise power sharing. This work introduces a hierarchical c...

Development and real-world deployment of a multi-agent system to support the op...

Despite the ongoing measures to support the development of Renewable Energy Communities (RECs), effectively managing energy production, consumption, and sharing, while balancing members’ needs, remains a major challenge. This paper presents a Multi-Agent System-based Community Energy Management System, designed to manage interactions and real-time energy exchanges within a REC to tackle the referred challenge i...

A Jittery Newborn with a Treatable Cause

Guia da Geologia do Alto de São Bento

Desde o ano 2000 que funciona no Alto de São Bento, nos antigos moinhos de vento recuperados para o efeito e na área adjacente, um espaço municipal destinado a atividades, tanto lúdico-pedagógicas como de promoção do conhecimento científico, em particular o património florístico e o geológico. Este guia da geologia resulta desse investimento. O Alto de São Bento, como é conhecido por todos os eborenses, constit...

sCD38 será a solução em doentes sob terapêutica com Daratumumab?

Enquadramento: O Daratumumab (anti-CD38) é um anticorpo monoclonal IgG amplamente utilizado no tratamento de doenças hemato-oncológicas como no caso do Mieloma Múltiplo (MM). O Daratumumab liga-se ao CD38 expresso pelos eritrócitos causando uma panaglutinação nos testes pré-transfusionais, nomeadamente Pesquisa de Anticorpos Irregulares (PAI) e Provas de Compatibilidade (PC) [1]. O reagente Ditiotreitol (DTT) t...

Retinal OCT-derived texture features as potential biomarkers for early diagnosi...

PURPOSE. Diabetic retinopathy (DR) is usually diagnosed many years after diabetes onset. Indeed, an early diagnosis of DR remains a notable challenge, and, thus, developing novel approaches for earlier disease detection is of utmost importance. We aim to explore the potential of texture analysis of optical coherence tomography (OCT) retinal images in detecting retinal changes in streptozotocin (STZ)-induced dia...

Energy sustainability in the ripening of traditional cheese: Renewable energy s...

Improving the energy efficiency of traditional production methods while preserving their cultural and economic value is a challenge aligned with the Sustainable Development Goals of the 2030 agenda. Refrigeration during cheese maturation is particularly energy-intensive, contributing significantly to greenhouse gas emissions and operating costs. An approach to make traditional cheese production more sustainable...

Novel Machine Learning-Based Approach for Determining Milk Clotting Time Using ...

The enzymatic coagulation of milk, crucial in cheese production, entails the hydrolysis of κ-casein and subsequent micelle aggregation. Conventional assessment standards, such as the Berridge method, depend on visual inspection and are susceptible to operator bias. Recent methods for the identification of milk-clotting time rely on optical, ultrasonic, and image-based technologies. In the present work, the comp...