The present study aimed to analyze cephalometric predictors of abnormal sella turcica (ST) in Sheehan Syndrome (SS) patients. An observational case-control study was performed with SS volunteers from the Endocrinology and Diabetology Service of the Walter Cantídio University Hospital (Brazil). The sample was composed of 32 patients allocated in two groups: case group (16 adult women diagnosed with SS) and contr...
Objective: Although hypothyroidism has been linked to oxidative stress, data regarding the relationship between thyroid hormone levels and oxidative stress is still inconsistent. This study was designed to evaluate the effect of levothyroxine replacement on oxidative stress in women with primary hypothyroidism. Design: A total of 25 female patients with primary hypothyroidism were included. Oxidative stress mar...
Hyperglycemia is a frequent complication and its prevalence occurs in up to 38% of hospitalized patients. Such condition may be due to previously known diabetes, stress responsive to associated diseases or treatments or it may due to diabetes only diagnosed during hospitalization. The presence of nosocomial hyperglycemia is associated with prolonged hospitalization time, increased demand for human resources and...
Background: Sheehan’s syndrome (SS) is one of the leading causes of hypopituitarism in developing countries. It occurs after postpartum necrosis of the pituitary gland, and it is considered a significant public health problem. This paper, apparently unpublished, aimed to perform an analysis on oral aspects in patients with SS. Material and Methods: A cross-sectional study was performed with 23 women diagnosed w...
Objetivo: o objetivo do estudo foi estabelecer a prevalência de lesões cutâneas em indivíduos com diagnóstico clínico de Neoplasia endócrina múltipla tipo 1 (NEM 1). Metodologia: realizamos exame dermatológico em 38 indivíduos e biópsia cutânea quando necessária para o diagnóstico. Resultados: dos 38 pacientes avaliados, 28 (73,7%) apresentavam uma ou mais lesões cutâneas, de predomínio no tronco e a idade médi...
The ageing process is associated with gradual decline in respiratory system performance. Anemia is highly prevalent among older adults and usually associated with adverse outcomes. Myelodysplastic syndromes (MDS) are a heterogeneous group of hematologic malignancies with increasing incidence with age and characterized by anemia and other cytopenias. The main objectives of this study were to evaluate respiratory...
Objective: A relation between transfusional IOL (iron overload), HFE status and oxidative damage was evaluated. Design, setting and participants: An observational cross-sectional study involving 87 healthy individuals and 78 patients with myelodysplastic syndromes (MDS) with and without IOL, seen at University Hospital of the Federal University of Ceará, Brazil, between May 2010 and September 2011. Methods: IOL...
Myelodysplastic syndromes (MDS) are group of stem cell disorders characterised by peripheral cytopaenias and a variable risk of progression to acute myeloid leukaemia. Most patients have anaemia and many develop transfusion dependence and iron overload (IOL), considered to be a negative independent prognostic factor associated with a higher risk of leukemic transformation and shorter survival.