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Pathogen-specific epitopes as epidemiological tools for defining the magnitude ...
Martins, Marcia V. S. B.; Guimarães, Marjorie M. da S.; Spencer, John S.; Hacker, Mariana A. V. B.; Costa, Luciana S.; Carvalho, Fernanda M.During recent years, comparative genomic analysis has allowed the identification of Mycobacterium leprae -specific genes with potential application for the diagnosis of leprosy. In a previous study, 58 synthetic peptides derived from these sequences were tested for their ability to induce production of IFN- c in PBMC from endemic controls (EC) with unknown exposure to M. leprae , household contacts of leprosy p...
Date: 2013
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Origin: Oasisbr