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Pseudomonas aestus Isolation from the Nasal Cavity of a Cat with Chronic Rhinitis

Abreu, Raquel; Mouro, Sofia; Guerreiro, Joana F.; Sousa, Sílvia A.; Leitão, Jorge H.; Pissarra, Hugo; Cunha, Eva; Tavares, Luís; Oliveira, Manuela

The Pseudomonas genus includes ubiquitous bacteria frequently described as animal and human opportunistic pathogens. A 9-year-old cat was referred for rhinoscopy at the Veterinary Hospital of the Faculty of Veterinary Medicine, University of Lisbon, Portugal, for an investigation of the chronic respiratory signs. Upon rhinoscopy, nasal and nasopharyngeal discharge were observed, and the nasal turbinates showed ...


Antitumoral and antimicrobial activities of block copolymer micelles containing...

Sousa, Andreia; Santos, Joana F.; Silva, Francisco; Sousa, Sílvia A.; Leitão, Jorge H.; Matos, António P.; Pinheiro, Teresa; Silva, Rafaela A. L.

Gold(III) bisdithiolate complexes have been reported as potential antimicrobial and antitumoral agents. The complex [Au(cdc)2]− (cdc=cyanodithioimido carbonate) displayed antimicrobial and outstanding antitumor activity against the ovarian cancer cells A2780 and A2780cisR, which are sensitive and resistant to cisplatin, respectively. However, poor water solubility may hamper its clinical use. Block copolymer mi...


Broad Spectrum Functional Activity of Structurally Related Monoanionic Au(III) ...

Le Gal, Yann; Filatre-Furcate, Agathe; Lorcy, Dominique; Jeannin, Olivier; Roisnel, Thierry; Dorcet, Vincent; Fontinha, Diana; Francisco, Denise

The biological properties of sixteen structurally related monoanionic gold (III) bis(dithiolene/diselenolene) complexes were evaluated. The complexes differ in the nature of the heteroatom connected to the gold atom (AuS for dithiolene, AuSe for diselenolene), the substituent on the nitrogen atom of the thiazoline ring (Me, Et, Pr, iPr and Bu), the nature of the exocyclic atom or group of atoms (O, S, Se, C(CN)...


Gold(III) bisdithiolate complexes: molecular conductors that also exhibit antic...

Marques, Fernanda; Sousa, Sílvia A.; Leitão, Jorge H.; Morais, Tânia S.; Le Gal, Yann; Lorcy, Dominique


Enhancing wastewater degradation and biogas production by intermittent operatio...

Nadais, Helena; Barbosa, Marta L.; Capela, Isabel; Arroja, Luís; Ramos, Christian G.; Grilo, André; Sousa, Sílvia A.; Leitão, Jorge H.

The present work establishes intermittent operation of UASB reactors as a novel form of enhancing the anaerobic degradation of complex wastewaters and its conversion to usable biogas. Results show that the average methane production rate is 25% higher with the intermittent operation than with the continuous mode, meaning that it could produce 25% more electricity or heat. The methanization efficiency obtained i...


A new methodology combining PCR, cloning, and sequencing of clones discriminate...

Ramos, Christian G.; Grilo, André M.; Sousa, Sílvia A.; Barbosa, Marta L.; Nadais, Helena; Leitão, Jorge H.

This work describes a methodology combining DNA extraction, polymerase chain reaction amplification with primers targeting 16S ribosomal RNA genes, cloning, and sequencing of clones previously analyzed by restriction fragment length polymorphism (RFLP), which can be applied to study the microbial diversity in a given habitat. The methodology allows the minimization of the sequencing effort, which is particularl...


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