Hipercolesterolemia Familiar (FH) é uma condição autossómica semidominante causada por variantes patogénicas ou provavelmente patogénicas nos genes LDLR, APOB e PCSK9. A FH pode apresentar-se na forma monoalélica (FH heterozigótica) ou bialélica (FH homozigótica). A forma homozigótica é mais rara e com fenótipo mais grave. Indivíduos com FH homozigótica geralmente apresentam hipercolesterolemia severa (LDL>400m...
Background: Sitosterolemia is a rare autosomal recessive lipid disorder caused by biallelic pathogenic variants in ABCG5 or ABCG8 genes. It is characterized by elevated plasma plant sterol concentrations, xanthomas, and an increased risk of premature cardiovascular disease. As happens with familial hypercholesterolemia (FH), sitosterolemia is subdiagnosed and is frequently confounded with FH, resulting in inapp...
Commercial solar thermal parabolic trough power plants use thermal oil as a heat transfer medium in the solar field. Within the framework of the HPS2 research project, funded by the BMWK (German Federal Ministry for Economic Affairs and Climate Action) and industry partners, the use of molten salt as heat transfer fluid (HTF) in the solar field is demonstrated, which could decrease levelized costs of electricit...
SOLARSCO2OL is an EU funded project that started in October 2020 with the following main objectives: to demonstrate a MW-scale recuperated supercritical CO2 (s CO2) power cycle operating from molten salts; to demonstrate a MW-scale molten salt electric heater to enable active hybridization of CSP and PV; and to investigate novel hybrid PV and CSP plants using sCO2 power blocks. The design of the key components ...
Various test results from operation since October 2021 at the Évora Molten Salt Platform (EMSP) with ternary HTF-salt are discussed. A focus is on solar pre-heating of receivers, collector improvements and testing of the ternary salt for its physical properties and its chemical stability for operation up to 500 °C.
Innovating through traditional products and resources is the main aim of HoST Lab Project located at the School of Management, Hospitality and Tourism of the University of the Algarve. A new lab and new multidisciplinary way of working, that which to be a reference for research and development applied to Culinary Tourism and Eno-gastronomic experiences associated with the Mediterranean Diet (MD). A very enrichi...
Background: The COVID-19 pandemic has put community pharmacists at the frontline of prevention, preparedness, response, and recovery efforts. Pharmacies had to reorganize and implement several different interventions and measures within a very short time frame. Objectives: 1) To map the current reported practice and trends and to review the literature on pharmacy-based interventions on COVID-19 provided in Euro...
A Autoavaliação (AA), Avaliação Interna (AI) e Avaliação Externa (AEE), são procedimentos orientados para a análise e melhoria das práticas, em contexto escolar. Esta última assenta, em aferições de conformidade normativa das atuações pedagógicas e didáticas e de administração e gestão, bem como de eficiência e eficácia das mesmas, alinhada com orientações da UE,UNESCO e OCDE, entidades/organizações internacion...
The main aim of this paper is the analysis of the third sector arts, culture and local development organisations (TSO) participation in the context of tourism planning and development and to understand the characteristics of its connections to the tourism sector in the region of the Algarve. The methodological strategy is anchored in a mix-methods approach applying qualitative techniques such as semi structured...