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Secondary metabolites of cyanobacteria from Cape Verde Archipelago act as NO do...

Morone, Janaína; Hentschke, Guilherme Scotta; Oliveira, Isabel Benta; Vasconcelos, Vítor; Martins, Rosário; Lopes, Graciliana; Martins, Rosário

Nitric oxide (NO) is a versatile mediator implicated in a variety of physiological processes, with the ultimate goal of maintaining organism homeostasis. In the present work, aqueous extracts from ten cyanobacteria strains isolated from the Cape Verde archipelago were explored as potential NO donors. None of the strains are toxin producers, as demonstrated by PCR and LC-MS analysis. The extracts were mainly com...


Colouring applications of microalgae and cyanobacteria photosynthetic pigments:...

Reimão, Mariana; Almeida, Liliana; Ramos, Cristiana; Eusébio, Nádia; Martins, Rosário; Silva, Manuela Vieira da; Vasconcelos, Vítor; Freitas, Marisa

Microalgae and cyanobacterial photosynthetic pigments possess immense potential for sustainable colouring applications in industries such as food, feed, cosmetics and textiles, primarily because of their vibrant colours, safety and eco-friendliness. These photosynthetic pigments align with the growing demand for eco-conscious products. However, substantial challenges persist at the industrial level, particularl...


Culinary plant-based decoctions: A promising approach for combatting neurodegen...

Grosso, Clara; Martins, Rosário; Delerue-Matos, Cristina; Martins, Rosario

This study aimed to assess the effectiveness of nutritional therapy in preventing or treating neurodegenerative disorders. To achieve this, decoctions from 5 culinary plants - turmeric (Curcuma longa L.), rosemary (Salvia rosmarinus Spenn.), lemon basil (Ocimum basilicum L. var. citriodorum), spearmint (Mentha spicata L.) and winter savory (Satureja montana L.) - were evaluated for their ability to combat react...


Bibliometric analysis towards industrial-scale use of Marine Algae and Lichens ...

Ouala, Oumaima; Essadki, Yasser; Oudra, Brahim; Khalloufi, Fatima El; Martins, Rosário; Martins, Rosario

The nutrient-rich composition of seaweeds and lichens makes them well-suited for agricultural applications. Their use as alternatives to synthetic fertilizers contributes to sustainable agricultural production, enabling farmers to adopt ecological practices while maintaining or increasing crop productivity. This review aims to highlight the status and trends of research, along with a literature analysis on the ...


Livro de Resumos: I Congresso Internacional em Enfermagem da ESS-IPVC: Investig...

Martins, Rosário; Graça, L.C.C.; Dias, Fátima; Calvinho, Salete

Date: 2024   |   Origin: Repositório Científico IPVC

Neuroprotective effects of cyanobacterial extracts

Rodrigues, Flávia; Grosso, Clara; Ferreira, Leonor; Vasconcelos, Vítor; Reis, Mariana; Martins, Rosário; Martins, Rosario

Neurodegenerative diseases (ND), namely Alzheimer’s disease (AD) affects millions of people worldwide. Despite their high incidence there is still no effective medical therapy. Cyanobacteria have been in the frontline of the search for therapies for ND. Several in silico, in vitro, and in vivo studies have provided support for the neuroprotective potential of cyanobacterial natural products, particularly in AD....


Evaluation of the anticancer potential of the macrofungus Pisolithus arhizus my...

Santos, Germana; Preto, Marco; Vasconcelos, Vítor; Martins, Rosário; Oliveira, Rui S.; Martins, Rosario

Macrofungi produce remarkable biomedical products that can make a significant contribution to health. Pisolithus arhizus is a fungal species of the phylum Basidiomycota. It is mainly found in association with the roots of some trees species, establishing a mutualistic relationship with them, facilitating the absorption of nutrients from the soil in exchange for carbohydrates produced by the host plant. As recen...


The neuroprotective role of cyanobacteria with focus on the anti-inflammatory a...

Rodrigues, Flávia; Reis, Mariana; Ferreira, Leonor; Grosso, Clara; Ferraz, Ricardo; Vieira, Mónica; Vasconcelos, Vítor; Martins, Rosário

Neurodegenerative diseases are linked to the process of neurodegeneration. This can be caused by several mechanisms, including inflammation and accumulation of reactive oxygen species. Despite their high incidence, there is still no effective treatment or cure for these diseases. Cyanobacteria have been seen as a possible source for new compounds with anti-inflammatory and antioxidant potential, such as polysac...


Nonthermal high-pressure microalgae extracts: A new source of natural ingredien...

Garcia, Mónica P.; Regueiras, Ana; Lopes, Graciliana; Matos, Gabriela; Silva, Lucília P. da; Cerqueira, Mariana T.; Cardoso, Helena; Correia, Nádia

Microalgae are one of the most prominent sources of ingredients for the cosmetic industry not only due to their diversity but, importantly, due to the low environmental impact in production and extraction. A sustainable extraction process requires the use of effective and environmentally friendly solvents that guarantee an extract with a relevant content and in high yields. In this work, Chlorella vulgaris, Nan...


Exploring the bioactive potential of Pisolithus (Basidiomycota): comprehensive ...

S. Oliveira, Rui; Preto, Marco; Santos, Germana; Silva, Ana Margarida; Vasconcelos, Vitor; Martins, Rosário

Addressing pressing health concerns, modern medical research seeks to identify new antimicrobials to combat drug resistance, novel molecules for cancer treatment, and antioxidants for inflammation-related diseases. Pisolithus (Basidiomycota) is a ubiquitous and widely distributed fungal genus in forest ecosystems, known for establishing ectomycorrhizal associations with a range of host plants, enhancing their g...


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