4 documents found, page 1 of 1
Understanding myoblast differentiation pathways when cultured on electroactive ...
Ribeiro, Sylvie Oliveira; Ribeiro, Clarisse; Martins, Vítor M.; Honoré, Bent; Neves, Maria Teresa; Gomes, Andreia C; Lanceros-Méndez, S.Electroactive materials allow to modulate cell-materials interactions and cell fate, leading to advanced tissue regeneration strategies. Nevertheless, their effect at the cellular level is still poorly understood. In this context, the proteome analysis of C2C12 cell differentiation cultured on piezoelectric polymer films with null average surface charge (non-poled), net positive surface charge (poled +) and net...
COVID-19 and Thromboinflammation: Is There a Role for Statins?
Ferrari, Filipe; Martins, Vítor M.; Teixeira, Marcelo; Santos, Raul D.; Stein, RicardoThe novel coronavirus disease (COVID-19) showed increased morbidity and mortality rates and worse prognosis in individuals with underlying chronic diseases, especially cardiovascular disease and its risk factors, such as hypertension, diabetes, and obesity. There is also evidence of possible links among COVID-19, myocardial infarction, and stroke. Emerging evidence suggests a pro-inflammatory milieu and hyperco...
Regulation of cell death induced by acetic acid in yeasts
Chaves, Susana Alexandra Rodrigues; Rego, António; Martins, Vítor M.; Pereira, Cátia Sofia Santos; Sousa, Maria João; Côrte-Real, ManuelaAcetic acid has long been considered a molecule of great interest in the yeast research field. It is mostly recognized as a by-product of alcoholic fermentation or as a product of the metabolism of acetic and lactic acid bacteria, as well as of lignocellulosic biomass pretreatment. High acetic acid levels are commonly associated with arrested fermentations or with utilization as vinegar in the food industry. Du...
Contacts in death: The role of the ER-mitochondria axis in acetic acid-induced ...
Martins, Vítor M.; Fernandes, Tânia R.; Afonso, Catarina B.; Lopes, Diana; Domingues, Maria R. M.; Côrte-Real, Manuela; Sousa, Maria JoãoEndoplasmic reticulum-mitochondria contact sites have been a subject of increasing scientific interest since the discovery that these structures are disrupted in several pathologies. Due to the emerging data that correlate endoplasmic reticulum-mitochondria contact sites function with known events of the apoptotic program, we aimed to dissect this interplay using our well-established model of acetic acid-induce...