16 documents found, page 1 of 2
Older-to-Older Living Kidney Transplantation: A New Paradigm
Figueiredo,Cátia Raquel; Sousa,Círia; Ventura,Sofia; Cruz,Gonçalo; Almeida,Manuela; Silvano,José; Malheiro,Jorge; Pedroso,Sofia; Martins,La SaleteABSTRACT Older to older living kidney transplantation is an acceptable alternative to avoid dialysis, improve quality of life and maintain favorable long-term outcomes of patients with end-stage kidney disease. However, the management of these patients is complex and the acceptance of older donors and recipients to kidney transplantation remains controversial. The older recipients usually have several comorbidi...
Late Onset of Pneumocystis jirovecii Pneumonia in Kidney Transplant: How Long i...
Sousa,Círia Leandra Martins de; Figueiredo,Cátia Raquel; Ventura,Sofia; Almeida,Manuela; Martins,La SaleteABSTRACT Pneumocystis jirovecii (PJ) opportunistic infections occur in immunocompromised patients impacting significantly hospitalizations and mortality. Trimethoprim-sulfamethoxazole (TMP-SMX) is universally used as prophylaxis of Pneumocystis jirovecii pneumonia (PJP) and therefore, this infection is rare condition in solid organ transplant (SOT) recipients. We present a case of a 46-years-old male, who recei...
Refractory ascites and graft dysfunction in early renal transplantation
Eusébio,Catarina Pereira; Correia,Sofia; Silva,Filipa; Almeida,Manuela; Pedroso,Sofia; Martins,La Salete; Diais,Leonídio; Queirós,JoséAbstract The occurrence of ascites after Renal Transplant (RT) is infrequent, and may be a consequence of surgical or medical complications. Case report: 61 year-old, male, history of arterial hypertension, tongue carcinoma and alcoholic habits 12-20g/day. He had chronic kidney disease secondary to autosomal dominant polycystic kidney disease, without hepatic polycystic disease. He underwent cadaver donor RT in...
Severe passenger lymphocyte syndrome associated to Rh antibodies after donor li...
Antunes,Marika Bini; Malheiro,Jorge; Dias,Leonidio; Martins,La Salete; Pedroso,Sofia; Almeida,Manuela; Henriques,Antonio Castro; Amil,MargaridaThe passenger lymphocyte syndrome may cause hemolytic anemia after bone marrow and solid organ transplantation when there is minor erythrocyte antigen incompatibility in the donor/recipient pair. Anemia is usually self-limiting, frequently related to ABO antibodies and rarely to Rh mismatches. We report a rare case of passenger B lymphocyte syndrome mediated by Rh antibodies occurring after a donor living renal...
Diagnosis of monoclonal gammopathy of renal significance
Correia,Sofia O; Santos,Sofia; Martins,La Salete; Santos,JosefinaMonoclonal gammopathies are a heterogeneous group of disorders characterized by clonal proliferation of immunoglobulin produced by B-lymphocytes or plasma cell clone. The term monoclonal gammopathy of renal significance (MGRS) was introduced to distinguish monoclonal gammopathies that result in the development of kidney disease from those that are benign. Screening for monoclonal immunoglobulin and an appropria...
Acute tubulointersticial nephritis with uveitis: A report of two cases
Silva,Filipa; Correia,Sofia O; Castro,Ana; Moreira,Carla; Santos,Sofia; Malheiro,Jorge; Santos,Josefina; Martins,La Salete; Cabrita,AntónioTubulointersticial nephritis and uveitis syndrome is an idiopathic and rare cause of acute kidney injury that should not overlooked, because it usually requires specific therapeutic interventions. We report two distinct cases: a young and an elder female. Both cases presented with unspecific constitutional symptoms but had different onset of renal and ocular involvement. Both were treated with topical and syste...
Malignancy after renal transplantation: a single-centre experience
Vieira,Pedro; Barreto,Patrícia; Pedroso,Sofia; Almeida,Manuela; Martins,La Salete; Dias,Leonídio; Henriques,António Castro; Cabrita,AntónioIntroduction: Malignancy management in renal transplant recipients is becoming a major factor affecting long-term patient survival. Thus, we intended to evaluate both incidence and prognosis of malignant diseases following renal transplantation at a single centre in Portugal. Methods: We studied retrospectively the 2,358 patients who underwent kidney transplantation (KT) between 1983 and 2014. Apart from descri...
BK virus nephropathy in kidney transplantation: A literature review following a...
Barreto,Patrícia; Almeida,Manuela; Dias,Leonídio; Vieira,Pedro; Pedroso,Sofia; Martins,La Salete; Henriques,António Castro; Cabrita,AntónioOver the last 15 years, better immunosuppressive drugs have decreased acute rejection rates in kidney transplantation but have also led to an increase in the incidence and impact of BK virus nephropathy. The authors report the case of a 62--year-old man submitted to a renal transplant of a deceased donor with an immunosuppression regimen free of rabbit anti -thymocyte globulin and tacrolimus, in whom BK nephrop...
Impact of pre-transplant anti-MICA sensitization in graft rejection and survival
Costa,Rui; Malheiro,Jorge; Tafulo,Sandra; Santos,Clara; Almeida,Manuela; Pedroso,Sofia; Martins,La Salete; Dias,Leonídio; Castro-Henriques,AntónioBackground: Evidence supporting deleterious effect of preformed major histocompatibility class I chain-related A (MICA) antibodies in rejection incidence and graft survival is still unclear. Methods: Retrospective analysis of 554 kidney transplanted patients. Comparison between positive or negative for MICA antibodies patients was performed to characterize sensitizing triggers. Further classification according ...
The first ABO-incompatible kidney transplantation performed in Portugal
Barreto,Patricia; Vieira,Pedro; Dias,Leonidio; Almeida,Manuela; Pedroso,Sofia; Martins,La Salete; Henriques,Antonio Castro; Bini,Marika; Cabrita,AntonioKidney transplantation is the optimal treatment of end -stage renal disease (ESRD) improving survival and quality of life for most recipients. In our country, potential living donors have been refused due to the ABO incompatibility barrier. However, ABO -incompatible living donor kidney transplant is presently common practice in several countries with good outcomes. The authors describe a case of a 49 -year -ol...