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Successful treatment of diffuse cutaneous leishmaniasis caused by Leishmania am...

Sampaio,Raimunda Nonata Ribeiro; Ferreira,Marina Freitas; Martins,Sofia Sales; Motta,Jorgeth de Oliveira Carneiro da

Abstract Diffuse cutaneous leishmaniasis is a rare universal disease associated with an inadequate host cell immune response, caused by different species: infantum, aethiopica, major, mexicana, and others, which presents the challenge of a poor therapeutic response. In Brazil, it is caused by L. amazonensis. A case confirmed by histopathology with an abundance of vacuolated macrophages full of amastigotes and l...

Date: 2021   |   Origin: Oasisbr

A randomized, open-label clinical trial comparing the long-term effects of milt...

Sampaio,Raimunda Nonata Ribeiro; Silva,Juliana Saboia Fontenele e; Paula,Carmen Dea Ribeiro de; Porto,Cláudia; Motta,Jorgeth de Oliveira Carneiro da

Abstract INTRODUCTION: The treatment of mucosal leishmaniasis (ML) is difficult due to the toxicity and route of administration of standard drugs. Miltefosine is an oral agent used for leishmaniasis treatment; however, no data exist regarding its use for ML in Brazil. In this study, we aimed to evaluate the efficacy of miltefosine for ML treatment compared to that of pentavalent antimonial in a pilot study. MET...

Date: 2019   |   Origin: Oasisbr

American cutaneous leishmaniasis triggered by electrocoagulation

Martins,Sofia Sales; Santos,Adriana de Oliveira; Lima,Beatriz Dolabela; Gomes,Ciro Martins; Sampaio,Raimunda Nonata Ribeiro

Abstract Cutaneous leishmaniasis is usually transmitted by infected phlebotomine sand fly bites that initiate local cutaneous lesions. Few reports in the literature describe other modes of transmission. We report a case of a previously healthy 59-year-old woman who underwent electrocoagulation to remove seborrheic keratosis confirmed by dermatoscopy. Three months later, a skin fragment tested positive for Leish...

Date: 2018   |   Origin: Oasisbr

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