Background: Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective: In this context, we decided to study certain consequences of the abundant cytokine release over the innate and adaptive immune systems, inflammation, and hemostas...
Background: An effective yellow fever (YF) vaccine has been available since 1937. Nevertheless, questions regarding its use remain poorly understood, such as the ideal dose to confer immunity against the disease, the need for a booster dose, the optimal immunisation schedule for immunocompetent, immunosuppressed, and pediatric populations, among other issues. This work aims to demonstrate that computational too...
Made available in DSpace on 2021-06-25T22:23:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-09-01; Sao Paulo State Univ UNESP, Aracatuba, SP, Brazil; Fed Inst Minas Gerais, Bambui, MG, Brazil; Fluminense Fed Univ, Niteroi, RJ, Brazil; Rene Rachou Inst, Belo Horizonte, MG, Brazil; Sao Paulo State Univ UNESP, Aracatuba, SP, Brazil
Funda??o Oswaldo Cruz (FIOCRUZ), Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico (CNPq), Funda??o de Amparo ? Pesquisa de Minas Gerais (FAPEMIG); Instituto Nacional de Ci?ncia e Tecnologia para Febres Hemorr?gicas Virais (INCT-FHV grant CNPq/CAPES/FAPESPA 573739/2008-0).; Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil / Universidade Federal...
Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG), BioManguinhos/FIOCRUZ, PROEP/IRR/FIOCRUZ, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico-CNPq; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Osw...
The effects of aging on the specific growth rate of Kluyveromyces lactis cultures, as a function of (NH4)2SO4 concentration, were evaluated. The growth kinetic parameters maximum specific growth rate and saturation constant for (NH4)2SO4 were calculated to be 0.44 h−1 and 0.15 mmol·L−1, respectively. Batch cultures were allowed to age for 16 days without influence of cell density or starvation. The specific gro...
Programa Nacional de Imuniza??es (PNI), Secretaria de Vigil?ncia em Sa?de (SVS), PDTIS, CNPq (472782/2009-6 and 475076/2013-3), CAPES, FAPEMIG and PROEP/CPqRR/FIOCRUZ for financial support. ACCA and JGCdR received financial support from CNPq MCTI/CNPq/2014.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG, Brazil.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte...
The methods currently available for genotype-specific diagnosis of T. cruzi infection still present relevant limitations, especially to identify mixed infection. In the present investigation, we have evaluated the performance of Chagas-Flow ATE-IgG2a test for early and late differential diagnosis of single and dual genotype-specific T. cruzi infections. Serum samples from Swiss mice at early and late stages of ...
Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG...
Fundação de Amparo a Pesquisa do Estado de Minas Gerais. Belo Horizonte, MG, Brazil; Universidade Federal de Minas Gerais. Departamento de Morfologia. Laboratório de Biologia das Interações Celulares. Belo Horizonte, MG, Brazil/Universidade Federal de Ouro Preto. Instituto de Ciências Exatas e Biológicas. Núcleo de Pesquisas em Ciências Biológicas/NUPEB Laboratório de Imunopatologia. Ouro Preto, MG, Brazil; Uni...