42 documents found, page 1 of 5

Morin-loaded chitosan-poloxamer hydrogel as an osteoinductive delivery system f...

Considering the search for new biocompatible intracanal medicaments that can preserve remaining cells and stimulate bone tissue repair in the periapical region, this study aimed to synthesize and characterize the physicochemical properties of morin-loaded chitosan-poloxamer hydrogel (MCP) as well as to evaluate its osteogenic potential. Morin hydrate (M) was loaded into chitosan-poloxamer (CP) hydrogel and the ...

Antimicrobial and wound healing effects associated to cytocompatibility and the...

Owing to its applications in both food and pharmaceutical industries honey is regarded as a functional product. This study evaluated 32 Portuguese monofloral honeys and their activity was compared with manuka honey 850 +. The antimicrobial activity was determined against Gram-positive and negative bacteria, and yeast. Antioxidant activity, wound healing ability, and cell viability were studied in the human kera...

In vitro biological activity and phenolic profile of selected portuguese monofl...

Portuguese monofloral honeys from carob tree, chestnut, bell heather, eucalyptus, incense, orange, and strawberry tree, were evaluated in vitro for antimicrobial, antioxidant, wound healing, and cell viability effect, compared to manuka honey 850+. Antimicrobial activity was determined against Gram+-and Gram- bacteria and yeast. Antioxidants, wound healing, and cell viability effects were studied in the Human K...

Biomimetic adhesive micropatterned hydrogel patches for drug release

The optimized physical adhesion between bees' leg hairs and pollen grains-whereby the latter's diameter aligns with the spacing between the hairs-has previously inspired the development of a biomimetic drug dressing. Combining this optimized process with the improved natural mussels' adhesion in wet environments in a dual biomimetic process, it is herein proposed the fabrication of a natural-derived micropatter...

New insights into the dermocosmetic potential of the red seaweed Gelidium corneum

This work addresses the potential of the red seaweed Gelidium corneum as a source of bioactive ingredients for skin health and wellness in response to the growing awareness regarding the significance of sustainable strategies in developing new nature-based dermocosmetic products. Hydroalcoholic extracts from the dried biomass were subjected to sequential liquid–liquid partitions, affording five different fracti...

Design and Characterization of an Ethosomal Gel Encapsulating Rosehip Extract

Rising environmental awareness drives green consumers to purchase sustainable cosmetics based on natural bioactive compounds. The aim of this study was to deliver Rosa canina L. extract as a botanical ingredient in an anti-aging gel using an eco-friendly approach. Rosehip extract was first characterized in terms of its antioxidant activity through a DPPH assay and ROS reduction test and then encapsulated in eth...

Cannabis-Based Products for the Treatment of Skin Inflammatory Diseases: A Time...

The use of natural products in dermatology is increasingly being pursued due to sustainability and ecological issues, and as a possible way to improve the therapeutic outcome of chronic skin diseases, relieving the burden for both patients and healthcare systems. The legalization of cannabis by a growing number of countries has opened the way for researching the use of cannabinoids in therapeutic topical formul...

Correction: Martins et al. Cannabis-Based Products for the Treatment of Skin In...

Nanotechnology-based sunscreens - a review

The daily use of sun protection is essential to prevent the damaging effect of incident solar ultraviolet (UV) radiation. Sunscreens are cosmetic products containing UV filters as active compounds, which are responsible for the absorption and/or reflection of UV radiation that might otherwise reach the skin surface. Sunscreen formulation has undergone a major technological transformation over the recent past, r...

On the progress of hydrogel-based 3D printing: Correlating rheological properti...

One of the exciting future directions in the 3D printing field is the development of innovative personalized smart constructions for bio-applications, including drug delivery, namely high-throughput drug screening and customized topical/oral administration of pharmaceuticals, as well as tissue engineering. In this context, hydrogels have emerged as a promising material that, when combined with extrusion 3D prin...