10 documents found, page 1 of 1
Comparison of pharmacist-led medication reconciliation and usual care on detect...
Palermo, Karen R.; Cotrina Luque, Jesús; Marto, Natália; Capoulas, Miriam; Santos, Cláudia; Figueiredo, Isabel V.; Castel-Branco, MargaridaBackground Medication reconciliation can reduce errors, particularly among elderly and polymedicated patients. The inclusion of pharmacists obtaining the best possible medication history can further improve the identification and resolution of discrepancies. Aim To compare a structured pharmacist-led medication reconciliation program with usual care on detecting and resolving discrepancies during hospital admis...
Efficacy of therapeutic interventions for idiopathic recurrent pregnancy loss
Lima, Jorge; Guerreiro, João; Ângelo-Dias, Miguel; Silvério Serra, Sofia; Costa, Teresa; Marto, Natália; de Pinho, João Feldman; Costa, JoãoFunding Information: The author(s) declare that financial support was received for the research and/or publication of this article. This study in the context of the \u201CWomen\u2019s Health and Maternal Fetal Research Group\u201D was partially co-financed by Hospital da Luz Lisboa under the initiative \u201CLuz Investiga\u00E7\u00E3o.\u201D The sponsor did not have any role in the study design, in the collecti...
Obstetric Intensive Care Admissions and Neonatal Outcomes
Rocha, Filipa Ramalho; Gonçalves, Tiago Neto; Xavier-Ferreira, Maria Inês; Laranjeira, Francisco; Magalhães, Gonçalo Meleiro; Lopes, Maria InêsFunding Information: This research was partially funded by the Hospital da Luz Lisboa under the initiative \u201CLuz Investiga\u00E7\u00E3o\u201D. The funding sources were not involved in the study design; collection, analysis and interpretation of data; the writing of the report; or the decision to submit the paper for publication. Publisher Copyright: © 2024 by the authors.; Background and Objectives: Materna...
Anti-HMGCR Immune-Mediated Myopathy: Literature Review Based in a Case Report
Baptista, Bernardo; Galaz Tavares, João; Marto, Natália; Bayão Horta, Alexandra; Roque, RafaelStatins are amongst the most prescribed drugs worldwide and they are generally safe. A rare but potentially serious adverse effect of statins’ therapy has been described– anti-3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (anti-HMGCR) immune-mediated necrotizing myopathy (IMNM) – that can occur years after the drug has beenstarted. We conducted a literature review after illustratinga typical case of anti-HMG...
In vivo phenotyping of sultia enzymes in man implications for precision medicine
Marto, NatáliaIntroduction:Sulfotransferase enzymes (SULT) catalyzesulfoconjugation of drugs, as well as endogenousmediators, gut microbiota metabolites and environmental xenobiotics. To address the limitedevidence on sulfonation activity from clinical research, we conceiveda clinical metabolic phenotypingmethod using paracetamol,a drug with significant metabolism by SULT1A1 and SULT1A3, as a probe substrate. Our aim was to ...
A simple method to measure sulfonation in man using paracetamol as probe drug
Marto, Natália; Morello, Judit; Antunes, Alexandra M.M.; Azeredo, Sofia; Monteiro, E.C.; SA, PereiraSulfotransferase enzymes (SULT) catalyse sulfoconjugation of drugs, as well as endogenous mediators, gut microbiota metabolites and environmental xenobiotics. To address the limited evidence on sulfonation activity from clinical research, we developed a clinical metabolic phenotyping method using paracetamol as a probe substrate. Our aim was to estimate sulfonation capability of phenolic compounds and study its...
Fármacos para tratamento da COVID-19
Marto, Natália; Monteiro, E.C.The novel severe acute respiratory syndrome coronavirus 2 is the cause of Coronavirus Disease 2019, a new illness with no effective treatment or vaccine that has reached pandemic proportions. In this document, we analyze how health authorities and agencies around the world position themselves regarding the off-label use of repurposed drugs or new investigational drugs to treat Coronavirus Disease 2019. We revie...
Anecdotal Response to Amphotericin in a Patient with Probable Susac Syndrome: I...
Gil-Gouveia, Raquel; Marto, Natália; Vilela, Pedro; Catarino, AnaSusac syndrome is a rare, probably immune-mediated endotheliopathy presenting with encephalopathy, sensorineural hearing loss and retinal arterial occlusions. A 33-year-old female with Susac syndrome was worsening despite high-dose steroids so a brain biopsy was performed which suggested a possible fungal infection. Treatment with amphotericin B resulted in prompt reversal of symptoms and radiological findings,...
Heat waves: health impacts.
Marto, NatáliaDuring the summer of 2003, record high temperatures were reported across Europe, causing thousands of casualties. Heat waves are sporadic recurrent events, characterised by intense and prolonged heat, associated with excess mortality and morbidity. The most frequent cause of death directly attributable to heat is heat stroke but heat waves are known to cause increases in all-cause mortality, specially circulato...
Ondas de calor: impacto sobre a saúde
Marto, NatáliaDurante o Verão de 2003, a Europa ocidental foi afectada por uma onda de calor sem precedentes, que provocou milhares de mortos. As ondas de calor são fenómenos climatéricos esporádicos mas recorrentes, caracterizadas por períodos de calor intenso,com duração de vários dias, e associadas a aumento da morbilidade e da mortalidade. A principal causa de morte directamente atribuível ao calor é o golpe de calor, ma...