34 documents found, page 1 of 4

"Mannose glycans as key players in trained immunity: A novel anti-tumoral catal...

Cell wall glycans isolated from microorganisms are long known to provoke strong immune responses piloted by innate immune cell populations, including monocytes, in the context of Trained Immunity (TI). However, the contribution of yeast-derived mannan in the reprogramming of monocytes remains ill-defined. Here, we demonstrated that TI is often accompanied by an altered gene expression profile of selected glycan...

Perturbações do Comportamento Alimentar: Casuística da Unidade de Internamento ...

INTRODUÇÃO: As perturbações do comportamento alimentar (PCA) são patologias com alta morbilidade e significativo impacto na vida de crianças e adolescentes. Trata-se de doenças biopsicossociais, envolvendo fatores de natureza individual, familiar e sociocultural. Apresentam elevada comorbilidade com outras perturbações psiquiátricas. As complicações orgânicas são comuns. O nosso objetivo foi caracterização dos ...

The Potential Role of Psychodrama Group Interventions for Child and Adolescents...

Delayed Diagnosis of Occult Phosphaturic Mesenchymal Tumor in the Foot

Phosphaturic mesenchymal tumors are the main cause of tumor-induced osteomalacia, a distinctive paraneoplastic syndrome mediated by overproduction of fibroblast growth factor 23, that leads to renal phosphate wasting and hypophosphatemia. Diagnosis of this mesenchymal tumors is difficult and usually delayed for several years. We present the case of a 70-years-old-male with generalized bone pain, multiple pathol...

Sternoclavicular Joint Septic Arthritis in a Healthy Adult: a Rare Diagnosis wi...

We report a case of complicated sternoclavicular joint septic arthritis in a previously healthy adult with no risk factors. An 83-year-old female presented to the emergency with a 1-week history of right shoulder pain followed by fever and prostration in the last 48 h. Computed tomography (CT) scan findings were consistent with right sternoclavicular joint (SCJ) septic arthritis complicated by periarticular abs...

Validation of the Ottawa Ankle Rules: Strategies for Increasing Specificity

Introduction: The majority of patients with ankle injuries undergo radiological examinations of the foot, ankle or both. The objective of this study was in the first place to validate the Ottawa Ankle Rules (OARs) for the population of our centre. Secondly, an attempt was made to identify parameters that contribute to improve the specificity of the method, with a view to reduce the need for patients to be expos...

SLC35A2-CDG: Novel variant and review

SLC35A2 encodes the X-linked transporter that carries uridine diphosphate (UDP)-galactose from the cytosol to the lumen of the Golgi apparatus and the endoplasmic reticulum. Pathogenic variants have been associated to a congenital disorder of glycosylation (CDG) with epileptic encephalopathy as a predominant feature. Among the sixty five patients described so far, a strong gender bias is observed as only seven ...

PROJECT FIGHT 2 - Development of an Edible Bait Vaccine to Control Rabbit Haemo...

PROJECT FIGHT-TWO - EDIBLE BAIT VACCINE FOR RABBIT HAEMORRHAGIC DISEASE VIRUS 2 (RHDV2) CONTROL IN WILD RABBITS Carina L. Carvalho1,2, Madalena Monteiro1, Paulo Carvalho1, Paula Mendonça1, Jorge Correia3, Berta São Brás, Conceição Peleteiro 2, Elsa Duarte3, António Mira3, Sandra Branco 3, António Roldão4, Margarida D. Duarte1,2 1-Instituto Nacional de Investigação Agrária e Veterinária Av. da República, Quinta ...

Intrauterine Blood Transfusion for Fetal Anemia Treatment – The Experience of 1...

Overview and aims: Intrauterine blood transfusion (IBT) is an established technique for the treatment of severe fetal anemia, increasing the survival of these fetuses. We aimed to describe the experience of a single center in pregnancies complicated with severe fetal anemia, that underwent IBT. Study design, Population, Methods: A retrospective cohort study was conducted from January 1996 to June 2014. Data wer...

Trisomy 15 Mosaicism: Challenges in Prenatal Diagnosis