3 documents found, page 1 of 1
Unveiling the traits of HER2-low breast cancer: a comparative analysis of IHC1+...
Correia, Jorge; Pulido, Catarina; Albuquerque, Joana; Prazeres, Gil; Margarido, Inês; Câmara, Mariana; Neto, Rita; Fernandes, Gonçalo; Godinho, JoãoBackground: Half of all breast cancer (BC) cases fall into the HER2-low category, defined as immunohistochemistry (IHC) 1+ or IHC 2+ in situ hybridization negative (ISH-). Two-thirds of these cases are IHC1+, while one-third is IHC2+/ISH-. New anti-HER2 antibody-drug conjugates (ADCs) have emerged as treatment options for metastatic or unresectable HER2-low BC patients. However, the heterogeneity between IHC1+ ...
Stereotactic radiosurgery in the intracranial benign neoplasms and malignant tu...
Mascarenhas, Francisco; Costa, M Sá da; Ortiz, M; Almeida, A; Carvalho, H; Ferreira, A Gonçalves; Cattoni, M BStereotactic Radiosurgery has proven to be during the last years the therapy of choice in more and more patients with benign and malignant brain tumors. The potential advantages comparatively to surgery and conventional radiotherapy made this technique a very important tool in the therapeutic armamentarium of neurooncology. This series presents the experience of treating more than 100 intracranial lesions with ...
Radiotherapy in supratentorial low grade gliomas.
Mascarenhas, Francisco; Matos, José António; Ortiz, Maximino; Pires, Maria Francisca; Grillo, Isabel MonteiroThe management of the supratentorial low-grade gliomas has been a question of great debate in our days and the best therapeutic approach is still to determinate. The improvements in the modern surgical techniques have made feasible greater degrees of resection and have lead to longterm progression-free survival remaining surgery as the mainstay of treatment for low grade gliomas. A considerable proportion of pa...