5 documents found, page 1 of 1
Serum creatinine trajectories in real-world hospitalized patients: clinical con...
Laszczyńska, O; Severo, M; Mascarenhas, J; Paiva, JA; Azevedo, AFluctuations in serum creatinine (SCr) during hospitalization may provide additional prognostic value beyond baseline renal function. This study aimed to identify groups of patients with distinct creatinine trajectories over hospital stay and assess them in terms of clinical characteristics and short-term mortality. This retrospective study included 35 853 unique adult admissions to a tertiary referral center b...
Prognostic Effect of Renal Function in Ambulatory Patients With Heart Failure a...
Mascarenhas, J; Laszczynska, O; Severo, M; Friões, F; Alvelos, M; Bettencourt, P; Pimenta, J; Azevedo, ABackground: Chronic kidney disease is a frequent comorbidity in heart failure (HF), associated with increased mortality. The impact of temporal evolution of kidney function in HF prognosis is largely unknown. We evaluated the effect of renal function over time in all-cause mortality among ambulatory patients with HF. Methods: We retrospectively analyzed data from 560 patients with HF with left ventricular systo...
Prognostic implications of diuretic dose in chronic heart failure
Martins, J; Lourenço, P; Araújo, JP; Mascarenhas, J; Lopes, R; Azevedo, A; Bettencourt, PBackground: Prognostic implications of diuretics dose are not completely understood. We aim to study the association between diuretic doses and long-term prognosis in patients with chronic stable heart failure (HF). Methods and Results: We conducted a retrospective cohort study of 244 patients followed at an outpatient HF clinic. Admission criteria were clinical stability in the previous 3 months and optimized ...
Clinical epidemiology of chronic obstructive pulmonary disease; [Epidemiologia ...
Mascarenhas, J; Bettencourt, P; Azevedo, AChronic obstructive pulmonary disease (COPD) is responsible for early morbidity and high mortality and significant costs to health systems. Smoking remains the main risk factor for COPD but additional factors, such as indoor and outdoor air pollution, occupational exposure and genetic susceptibility are increasingly recognized. Th e burden of COPD has been difficult to estimate owing to the multiple definitions...
Coexisting chronic obstructive pulmonary disease and heart failure: Implication...
Mascarenhas, J; Azevedo, A; Bettencourt, PPurpose of review: Chronic obstructive pulmonary disease (COPD) and heart failure are prevalent comorbidities affecting a huge proportion of the world population, responsible for significant morbidity and mortality. Their coexistence is more frequent than previously recognized and poses important diagnostic and therapeutic challenges. Prognosis of patients with concurrent heart failure and COPD has not been com...