21 documents found, page 1 of 3
Depression in the Paediatric Population: Current Therapeutic Context and Challe...
Rodrigues, Ana Rita; Palavra, Filipe; Bell, Victoria; Mascarenhas-Melo, Filipa; Almeida, Luis; Veiga, FranciscoMajor depression, as a clinical condition associated with the highest rate of disability worldwide, presents very particular contours when it affects the pediatric population. The biochemical and pathophysiological changes associated with depression are naturally influenced by socioeconomic aspects and family dynamics, which contributes to great heterogeneity and variability in the symptoms expressed by childre...
Multifunctional hydrogels-based therapies for chronic diabetic wound healing
Duarte, Joana; Mascarenhas-Melo, Filipa; Pires, Patrícia C.; Veiga, Francisco; Paiva-Santos, Ana CláudiaChronic diabetic wounds persist as a healthcare challenge and therefore require the use of innovative therapeutic approaches. Among emerging solutions, hydrogels stand out as a promising avenue for diabetic wound healing due to their unique properties and versatile applications, capable of addressing the complex and challenging microenvironment that characterizes such wounds. In this work, through a detailed an...
Nanomaterials in Cosmetics: An Outlook for European Regulatory Requirements and...
Ferreira, Laura; Pires, Patrícia C.; Fonseca, Mariana; Costa, Gustavo; Giram, Prabhanjan Shridhar; Mazzola, Priscila Gava; Bell, VictoriaThe use of materials and products that improve appearance and provide comfort and well-being goes back to the beginning of civilization. Cosmetics is an evolving market that has increasingly focused on innovative technological approaches. Nanotechnology is one of the most revolutionary and promising fields for the development of novel and enhanced cosmetic products, owing to the remarkable multifunctional chara...
The Role of Cyclodextrins in COVID-19 Therapy-A Literature Review
Almeida, Beatriz C.; Domingues, Cátia; Mascarenhas-Melo, Filipa; Silva, Inês; Jarak, Ivana; Veiga, Francisco; Figueiras, AnaCoronavirus disease-19 (COVID-19) emerged in December 2019 and quickly spread, giving rise to a pandemic crisis. Therefore, it triggered tireless efforts to identify the mechanisms of the disease, how to prevent and treat it, and to limit and hamper its global dissemination. Considering the above, the search for prophylactic approaches has led to a revolution in the reglementary pharmaceutical pipeline, with th...
Dermatological Bioactivities of Resveratrol and Nanotechnology Strategies to Bo...
Mascarenhas-Melo, Filipa; Araújo, André Gonçalves; Rodrigues, Márcio; Mathur, Ankita; Gonçalves, Maria Beatriz S.; Tanwar, Kalpita; Heidarizadeh, FaribaResveratrol is a polyphenolic phytoalexin, whose main natural sources are red grapes, red wine, berries, and peanuts. When applied to the skin, resveratrol evidences a good penetrating capacity and low degradation compared to the oral route, allowing for a longer and improved topical effect. This bioactive molecule has been gaining interest in dermo-pharmacy and cosmetics for the prevention and treatment of ski...
Cyclodextrin-based dermatological formulations: Dermopharmaceutical and cosmeti...
Ferreira, Laura; Mascarenhas-Melo, Filipa; Rabaça, Sofia; Mathur, Ankita; Sharma, Ankur; Giram, Prabhanjan S.; Pawar, Kiran D.; Rahdar, AbbasThe progress in new delivery systems for active ingredients has boosted the dermopharmaceutical and cosmetic fields by allowing formulations to display enhanced skin permeation capabilities. Cyclodextrins (CDs) are cyclic oligosaccharides able to form host-guest inclusion complexes with guest active molecules, resulting in improved physicochemical properties of such molecules. The incorporation of CDs in dermop...
Rosacea Topical Treatment and Care: From Traditional to New Drug Delivery Systems
Paiva-Santos, Ana Cláudia; Gonçalves, Tatiana; Peixoto, Diana; Pires, Patrícia C.; Velsankar, K.; Jha, Niraj Kumar; Chavda, Vivek P.Rosacea is a multifactorial chronic inflammatory dermatosis characterized by flushing, nontransient erythema, papules and pustules, telangiectasia, and phymatous alterations accompanied by itching, burning, or stinging, the pathophysiology of which is not yet fully understood. Conventional topical treatments usually show limited efficacy due to the physical barrier property of the skin that hinders skin penetra...
: The smoking cessation process and the pharmacist’s contribution: impact on pu...
Lima, Adriana; Mascarenhas-Melo, Filipa; Bell, VictoriaO tabagismo é considerado um fator de risco de inúmeras doenças e afeta quer a população fumadora, quer a não fumadora. Este hábito é a principal causa evitável de doenças crónicas, perda de qualidade de vida e morte no mundo. Desta forma, é considerado um problema de saúde pública que afeta toda a população. O tabaco pode ser consumido de diversas formas e é causador de dependência quer física, quer psicológic...
Characterisation of institutionalised Portuguese older adult fallers: is there ...
Ferreira, Carina Ramos; Mascarenhas-Melo, Filipa; Rodrigues, Ana Rita; Lima, Maria João Reis; Pinheiro, João Páscoa; Chaves, ClaúdiaFalls are a major public health issue, given their prevalence and social impact. Older adults living in long-term care facilities (LTCF) are at greater risk of injury resulting from a fall due to multiple factors, such as nutritional, functional/cognitive impairment, postural instability, polypharmacy, and the presence of potentially inappropriate medications (PIMs). Medication management in LTCF is complex and...
Pharmacist Intervention in Portuguese Older Adult Care
Rodrigues, Ana Rita; Teixeira-Lemos, Edite; Mascarenhas-Melo, Filipa; Lemos, Luis Pedro das Neves Teixeira de; Bell, VictoriaHealthy ageing has become one of the most significant challenges in a society with an increasing life expectancy. Older adults have a greater prevalence of chronic disease, with the need for multiple medications to appropriately control these issues. In addition to their health concerns, ageing individuals are prone to loneliness, dependence, and economic issues, which may affect their quality of life. Governme...