4 documents found, page 1 of 1
Silver complexes for tuberculosis treatment: a short review
Biagioni,Bruno Torquato; Cavicchioli,Maurício; Massabni,Antonio CarlosThis paper is a brief review of silver complexes that have been identified as antibacterial drugs with promising use for the treatment of tuberculosis (TB). This treatment aims to cure and discontinue the transmission of the disease. The excessive and inappropriate use of drugs has jeopardized the effectiveness of antibiotics for the TB treatment, bringing bacterial resistance to them. To achieve these objectiv...
SYNTHESIS, CHARACTERIZATION, DFT MODELING AND IN VITRO ANTIMYCOBACTERIAL ACTIVI...
Paris Junior,José Alberto; Cavicchioli,Maurício; Machado,Rachel Temperani Amaral; Pavan,Fernando Rogério; Nakahata,Douglas Hideki; Corbi,Pedro PauloIn the present work, a silver(I) complex with the antimycobacterial drug isoniazid (inh) is described. Elemental and thermogravimetric analyses confirmed a 1:1 metal:ligand ratio for the silver-isoniazid (Ag-inh) complex with molecular composition AgC6H7N3O·NO3. Infrared (IR) analysis suggests a bidentate coordination of isoniazid to silver by the nitrogen of the NH2 group and by the oxygen of the C=O group, an...
Síntese e reatividade de complexos platina-trifenilestibina: uma revisão biblio...
Barbiéri,Roberto Santos; Bellato,Carlos Roberto; Massabni,Antonio CarlosThis article deals with synthesis and reactivity of complexes with triphenylstibine (SbPh3) as the ligand. A comparative study of analogous complexes of triphenylphosphine (PPh3) and triphenylarsine (AsPh3) with platinum in the oxidation states zero, two and four is included. The bibliographic revision includes publications since 1936, when the first Pt(II) complex with triphenylstibine was described.
Quatro décadas de química na UNESP/Araraquara
Massabni,Antonio Carlos; Ernandes,José Roberto; Melios,Cristo BladimirosThis article describes the history of four decades of activities in the Institute of Chemistry of Araraquara, UNESP: the beginning, the evolution of undergraduate and graduate courses and the infra-structure of teaching and research.