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The potential of selected natural products as biofilm control agents and antibi...

Massano, Francisca; Sousa, Mariana; Borges, Anabela; Simões, Manuel

Background: The emergence of multidrug-resistant bacteria, especially within biofilms, poses a serious public health threat and represents a major challenge for effective infection management. Traditional antibiotics often fail to effectively treat bacteria and biofilm-associated infections, prompting the need for novel strategies to combat bacterial resistance and biofilm formation. Natural compounds, such as ...

Date: 2025   |   Origin: Scientific Letters

Coaggregation dynamics in drinking water biofilms and implications for chlorine...

Afonso, Ana C.; Gomes, Inês B.; Massano, Francisca; Saavedra, Maria J.; Simões, Manuel; Simões, Lúcia Chaves

Biofilms in drinking water (DW) systems persistently challenge traditional disinfection methods due to intricate microbial interactions, with coaggregation playing a crucial role in forming multispecies biofilms. This study examined the implications of coaggregation on tolerance towards sodium hypochlorite (NaOCl) disinfection. Dual-species biofilms were formed for seven days on polyvinyl chloride coupons, comp...


Development of a hydrogel with antioxidant and antibacterial properties loaded ...

S. Teixeira, Lília; Sousa, Mariana; Massano, Francisca; Simões, Manuel; Borges, Anabela

Background: Chronic wound infections are an emerging issue affecting millions of people globally, with profound psychological and socio-economic consequences [1]. Nonetheless, effective treatments to promote wound healing remain scarce [2]. Natural hydrogels appear as promising alternative wound dressings due to exudate absorption capacity and inherent wound-healing properties [3]. Objective: This study explore...

Date: 2024   |   Origin: Scientific Letters

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