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Preserving cognitive function in patients with Alzheimer's disease: The Alzheim...

Liu, Jie; Van Beusekom, Heleen; Bu, Xian‐Le; Chen, Gong; Rosado de Castro, Paulo Henrique; Chen, Xiaochun; Chen, Xiaowei; Clarkson, Andrew N.

The global trend toward aging populations has resulted in an increase in the occurrence of Alzheimer's disease (AD) and associated socio-economic burdens. Abnormal metabolism of amyloidâ β (Aβ) has been proposed as a signiï¬ cant pathomechanism in AD, supported by results of recent clinical trials using antiâ Aβ antibodies. Nonetheless, the cognitive beneï¬ ts of the current treatments are limited. The etiol...


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