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Local and systemic immunomodulatory mechanisms triggered by Human Papillomaviru...

Alvarez, Karla Lucia Fernandez; Beldi, Mariana Carmezim; Sarmanho, Fabiane; Rossetti, Renata Ariza Marques; Silveira, Caio Raony Farina

Cervical cancer is the last stage of a series of molecular and cellular alterations initiated with Human Papillomavirus (HPV) infection. The process involves immune responses and evasion mechanisms, which culminates with tolerance toward tumor antigens. Our objective was to understand local and systemic changes in the interactions between HPV associated cervical lesions and the immune system as lesions progress...

Date: 2017   |   Origin: RepositóriUM - Universidade do Minho
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