5 documents found, page 1 of 1
Genetic Contribution of the Adrenergic, Cholinergic, and Serotonergic Systems t...
Inácio, Ângel; Aguiar, Laura; Carrilho, Raquel; Pires, Patrícia; Ferreira, Joana; Coelho, Luís; Mascarenhas, Mário Rui; Sardinha, Luís; Bilhim, TiagoFunding Information: study, we conclude that the ADBR2 and CHRNA5 genes have a relevant role in the development of leiomyoma. This role appears to be enhanced by the epistatic relationship with the genes HTR2A and SLC6A4. This study, confirms the involvement of the Autonomous Nervous System in tumor biology, along with the genetics of the mechanisms, involved in chronic stress. By highlighting and helping to el...
Differences in the genotype frequencies of genes related to blood pressure regu...
Aguiar, Laura; Semente, Ildegário; Ferreira, Joana; Carvalho, Andreia; Silva, Alda P.; Caroça, Cristina; Caria, Helena; Damasceno, AlbertinoFunding Information: The authors are grateful to all study participants and would like to thank the Instituto de Investiga??o Cient?fica Bento da Rocha Cabral for financial support. Publisher Copyright: © 2021 Aguiar L et al.; Background: Since the emergence of the genus Homo, hominids have occupied a wide variety of environments, facing different selective pressures. Objectives: The aim this study is to compar...
Towards a global perspective of environmental health
Virgolino, Ana; Antunes, Francisco; Santos, Osvaldo; Costa, Andreia; de Matos, Margarida Gaspar; Bárbara, Cristina; Bicho, Manuel; Caneiras, CátiaFunding Information: Funding: This research was funded by Fundação para a Ciência e a Tecnologia, grant number UIDB/04295/2020 and UIDP/04295/2020. Funding Information: This research was funded by Funda??o para a Ci?ncia e a Tecnologia, grant number UIDB/04295/2020 and UIDP/04295/2020. Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.; Environmental health is at the intersection bet...
Effects of combined training with different intensities on vascular health in p...
Magalhães, João P.; Melo, Xavier; Correia, Inês R.; Ribeiro, Rogério T.; Raposo, João; Dores, Helder; Bicho, Manuel; Sardinha, Luís B.The authors declare that the research was conducted in the absence of any commercial or fnancial relationships that could be construed as a potential competing interest. JM and RTR are supported by a scholarship from the Portuguese Foundation for Science and Technology (JM grant: SFRH/ BD/85742/2012, RTR grant: SFRH/BPD/110426/2015). This work is also fnanced by a national grant through the FCT—Fundação para a ...
Estudo Português de miocardiopatias dilatadas familiares. Estudo FATIMA
Martins, Elisabete; Silva-Cardoso, José; Bicho, Manuel; Bourbon, Mafalda; Ceia, Fatima; Rebocho, M. José; Moura, Brenda; Fonseca, CândidaDilated cardiomyopathy (DCM) is a myocardial disease, characterized by ventricular dilatation and impaired systolic function, that in more than 30% of cases has a familial or genetic origin. Given its age-dependent penetrance, DGM frequently manifests in adults by signs or symptoms of heart failure, arrhythmias of sudden death. The predominant mode of inheritance is autosomal dominant, and in these cases mutati...