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Shaping of Hepatic Ischemia/Reperfusion Events: The Crucial Role of Mitochondria

Teodoro, João S.; Silva, Rui T. da; Machado, Ivo; Panisello-Roselló, Arnau; Roselló-Catafau, Joan; Rolo, Anabela P.; Palmeira, Carlos M.

Hepatic ischemia reperfusion injury (HIRI) is a major hurdle in many clinical scenarios, including liver resection and transplantation. Various studies and countless surgical events have led to the observation of a strong correlation between HIRI induced by liver transplantation and early allograft-dysfunction development. The detrimental impact of HIRI has driven the pursuit of new ways to alleviate its advers...


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