10 documents found, page 1 of 1
Three-Dimensional Impression of Biomaterials for Alveolar Graft: Scoping Review
Francisco, Inês; Basílio, Ângela; Ribeiro, Madalena Prata; Nunes, Catarina; Travassos, Raquel; Marques, Filipa; Pereira, Flávia; Paula, Anabela BaptistaCraniofacial bone defects are one of the biggest clinical challenges in regenerative medicine, with secondary autologous bone grafting being the gold-standard technique. The development of new three-dimensional matrices intends to overcome the disadvantages of the gold-standard method. The aim of this paper is to put forth an in-depth review regarding the clinical efficiency of available 3D printed biomaterials...
Bone Mineral Density through DEXA and CBCT: A Systematic Review with Meta-Analysis
Francisco, Inês; Nunes, Catarina; Pereira, Flávia; Travassos, Raquel; Ribeiro, Madalena Prata; Marques, Filipa; McEvoy, Mariana; Santos, MarianaDual-energy X-ray absorptiometry is used to determine bone density in several pathologies, namely osteoporosis and fracture risk in post-menopausal women. The aim of this study was to identify, appraise and synthesize all available evidence about the correlation between Dual Energy X-ray Absorptiometry (DEXA) and Cone Beam Computed Tomography (CBCT) techniques through a systematic review. A systematic literatur...
The Biological Effects of 3D Resins Used in Orthodontics: A Systematic Review
Francisco, Inês; Paula, Anabela Baptista; Ribeiro, Madalena; Marques, Filipa; Travassos, Raquel; Nunes, Catarina; Pereira, Flávia; Marto, Carlos MiguelThree-dimensional (3D) resin medical-dental devices have been increasingly used in recent years after the emergence of digital technologies. In Orthodontics, therapies with aligners have gained popularity, mainly due to the aggressive promotion policies developed by the industry. However, their systemic effects are largely unknown, with few studies evaluating the systemic toxicity of these materials. The releas...
What Is the Most Effective Technique for Bonding Brackets on Ceramic-A Systemat...
Francisco, Inês; Travassos, Raquel; Nunes, Catarina; Ribeiro, Madalena; Marques, Filipa; Pereira, Flávia; Marto, Carlos Miguel; Carrilho, EuniceBackground: There has been an increase in demand for orthodontic treatment within the adult population, who likely receive restorative treatments using ceramic structures. The current state of the art regarding the most effective method to achieve an appropriate bond strength of brackets on ceramic surfaces isn't consensual. This systematic review aims to compare the available surface treatments to ceramics and...
Application of Three-Dimensional Digital Technology in Orthodontics: The State ...
Francisco, Inês; Ribeiro, Madalena Prata; Marques, Filipa; Travassos, Raquel; Nunes, Catarina; Pereira, Flávia; Caramelo, FranciscoThree-dimensional technologies are one of the most recent and relevant advancements in the field of Dentistry. These systems, including intraoral scans, 3D imaging exams (CAT scan, CBCT and MRI), CAD/CAM 3D printing devices and 3D computer software, have enabled clinicians to greatly improve patient care along with reducing treatment planning time. The present descriptive study aims to explore possible applicat...
KRAS as a modulator of the inflammatory tumor microenvironment: therapeutic imp...
Pereira, Flávia; Ferreira, Anabela; Reis, Celso Albuquerque; Sousa, Maria João; Oliveira, Maria José; Preto, AnaKRAS mutations are one of the most frequent oncogenic mutations of all human cancers, being more prevalent in pancreatic, colorectal, and lung cancers. Intensive efforts have been encouraged in order to understand the effect of KRAS mutations, not only on tumor cells but also on the dynamic network composed by the tumor microenvironment (TME). The relevance of the TME in cancer biology has been increasing due t...
Crucial role of oncogenic KRAS mutations in apoptosis and autophagy regulation:...
Ferreira, Anabela; Pereira, Flávia; Reis, Celso; Oliveira, Maria José; Sousa, Maria João; Preto, AnaKRAS, one of the RAS protein family members, plays an important role in autophagy and apoptosis, through the regulation of several downstream effectors. In cancer cells, KRAS mutations confer the constitutive activation of this oncogene, stimulating cell proliferation, inducing autophagy, suppressing apoptosis, altering cell metabolism, changing cell motility and invasion and modulating the tumor microenvironme...
A New Orthodontic-Surgical Approach to Mandibular Retrognathia
Vale, Francisco; Queiroga, Joana; Pereira, Flávia; Ribeiro, Madalena; Marques, Filipa; Travassos, Raquel; Nunes, Catarina; Paula, Anabela Baptista(1) Background: Mandibular deficiency is one of the most common growth disorders of the facial skeleton. Recently, distraction osteogenesis has been suggested as the treatment of choice for overcoming the limitations of conventional orthognathic surgery; (2) Methods: A new custom-manufactured dental-anchored distractor was built and anchored in the first molar and lower canine. It consists of a stainless-steel ...
Mulheres em altos cargos de empresas familiares: experiências de sucessão e des...
Marques, Ana Paula; Pereira, FláviaInicia-se este capítulo explorando a importância de se enunciar os preconceitos ou estereótipos de género que conduzem à instituição de “regimes normativos” presentes nas organizações que expressam, por isso, desigualdades de género incrustados nas suas estruturas, interações e culturas dominantes. Em seguida, faz-se uma breve revisitação do processo recente de qualificação do(a) fundador(a) à frente das empres...
The Yeast Saccharomyces cerevisiae as a Model for Understanding RAS Proteins an...
Cazzanelli, Giulia; Pereira, Flávia; Alves, Sara; Francisco, Rita; Azevedo, Luísa; Dias Carvalho, Patrícia; Almeida, Ana; Côrte-Real, ManuelaThe exploitation of the yeast <i>Saccharomyces cerevisiae</i> as a biological model for the investigation of complex molecular processes conserved in multicellular organisms, such as humans, has allowed fundamental biological discoveries. When comparing yeast and human proteins, it is clear that both amino acid sequences and protein functions are often very well conserved. One example of the high degree of cons...