3 documents found, page 1 of 1
Yap induces osteoblast differentiation by modulating Bmp signalling during zebr...
Brandão, Ana S.; Bensimon-Brito, Anabela; Lourenço, Raquel; Borbinha, Jorge; Soares, Ana Rosa; Mateus, Rita; Jacinto, AntonioFunding This work was funded by Fundaçãõ o para a Ciência e a Tecnologia (FCT; PTDC/BIMMED/0659/2014; SFRH/BD/51990/2012 to A.S.B.; SFRH/BD/131929/2017 to J.B.; PD/BD/106052/2015 to A.R.S.). R.L. was supported by the FCT in the context of a program contract (D.L. no. 57/2016). Zebrafish maintenance was supported by Congento LISBOA-01-0145-FEDER-022170, co-financed by FCT (Portugal) and Lisboa2020, under the PO...
Control of tissue growth by Yap relies on cell density and F-actin in zebrafish...
Mateus, Rita; Lourenço, Raquel; Fang, Y.; Brito, G; Farinho, Ana; Valerio, Fabio; Jacinto, AntonioThis work was supported by funding from Fundacao para a Ciencia e Tecnologia [SFRH/BD/62126/2009, PTDC/BEX-BID/1176/2012]; and Agence Nationale de la Recherche [ANR-11-BSV5-0021].; Caudal fin regeneration is characterized by a proliferation boost in the mesenchymal blastema that is controlled precisely in time and space. This allows a gradual and robust restoration of original fin size. However, how this is est...
In Vivo Cell and Tissue Dynamics Underlying Zebrafish Fin Fold Regeneration
Mateus, Rita; Pereira, Telmo; Sousa, Sara; de Lima, Joana Esteves; Pascoal, Susana; Saúde, Leonor; Jacinto, AntonioBackground: Zebrafish (Danio rerio) has a remarkable capacity to regenerate many organs and tissues. During larval stages the fin fold allows the possibility of performing long time-lapse imaging making this system very appealing to study the relationships between tissue movements, cell migration and proliferation necessary for the regeneration process. Results: Through the combined use of transgenic fluorescen...