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Determinants of the Sympatric Host-Pathogen Relationship in Tuberculosis

David, Susana; Mateus, A.R.A.; Duarte, Elsa; Albuquerque, José Maria; Portugal, Clara; Sancho, Luísa; Lavinha, João; Gonçalves, Guilherme

Major contributions from pathogen genome analysis and host genetics have equated the possibility of Mycobacterium tuberculosis co-evolution with its human host leading to more stable sympatric host–pathogen relationships. However, the attribution to either sympatric or allopatric categories depends on the resolution or grain of genotypic haracterization. We explored the influence on the sympatric host-pathogen ...


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