A pericardite constritiva, manifesta-se como uma doença rara, que se caracteriza pela perda de distensibilidade do pericárdio, secundária a um processo inflamatório. A tuberculose (TB) é a principal causa de pericardite constritiva nos países de baixo rendimento e nos doentes imunodeprimidos, nomeadamente, com infeção por vírus da imunodeficiência humana (VIH). Os autores relatam o caso de um homem de 24 anos, ...
The COVID-19 pandemic has driven immunity acquisition through infection or vaccination, leading to SARS-CoV-2 antibodies. This study introduces a colorimetric biosensor for COVID-19 immunity screening using Virus-Like Particles (VLPs) with SARS-CoV-2 spike protein motifs on a cellulose carrier. The cellulose was chemically modified with DSS to secure the VLPs, verified via FTIR. Detection utilized the Bradford ...
Acute pancreatitis is a common, heterogeneous, and unpredictable disease with significant associated morbidity and mortality. Early recognition and timely management of this condition are essential to prevent complications. It is characterized by pancreatic inflammation, most commonly associated with increased serum amylase and lipase levels. However, this criterion is not a mandatory requirement for the diagno...
A endocardite fúngica é uma condição rara e potencialmente fatal, em geral causada pelas espécies Candida e Aspergillus. Incide maioritariamente em doentes imunossuprimidos, com história pregressa de endocardite, ou com próteses ou dispositivos intracardíacos. As terapêuticas antifúngicas e cirúrgicas são essenciais pelo intuito curativo e evicção de fenómenos embólicos. São raros os casos de sucesso tratados c...
Dendritic cells (DCs) are the most specialized and proficient antigen-presenting cells. They bridge innate and adaptive immunity and display a powerful capacity to prime antigen-specific T cells. The interaction of DCs with the receptor-binding domain of the spike (S) protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a pivotal step to induce effective immunity against the S protei...
Given the pandemic situation, there is an urgent need for an accurate test to monitor antibodies anti-SARS-CoV-2, providing crucial epidemiological and clinical information to monitor the evolution of coronavirus disease in 2019 (COVID-19) and to stratify the immunized and asymptomatic population. Therefore, this paper describes a new cellulosebased test strip for rapid and cost-efective quantitative detection ...
Given the pandemic situation, there is an urgent need for an accurate test to monitor antibodies anti-SARS-CoV-2, providing crucial epidemiological and clinical information to monitor the evolution of coronavirus disease in 2019 (COVID-19) and to stratify the immunized and asymptomatic population. Therefore, this paper describes a new cellulose-based test strip for rapid and cost-effective quantitative detectio...
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