Delivering a project has several challenges to be addressed, and to mitigate them, multiple approaches have arisen and suggested as best practices to stakeholders’ satisfaction. This research presents a proposal to manage communication inside a virtual project team, adapting concepts from traditional and agile approaches into a hybrid framework, created using the action research spiral approach to evaluate the ...
Measurement of muscle strength is fundamental for the management of patients with myotonic dystrophy type 1 (DM1). Nevertheless, guidance on this topic is somewhat limited due to heterogeneous outcome measures used. This systematic literature review aimed to summarize the most frequent outcome measures to assess muscle strength in patients with DM1. We searched on Pubmed, Web of Science and Embase databases. Ob...
Myotonic dystrophy type 1 (DM1) is an autosomal dominant hereditary and multisystemic disease, characterized by progressive distal muscle weakness and myotonia. Despite huge efforts, the pathophysiological mechanisms underlying DM1 remain elusive. In this review, the metabolic alterations observed in patients with DM1 and their connection with lipin proteins are discussed. We start by briefly describing the epi...
The market environment and customer requirements are changing at an increasing pace. It is crucial that organizations remain competitive by embracing new challenges. These changes require different and more agile leadership, mindset and collaboration, including more team empowerment. With the constant increment of projects and programs, organizations have to adopt new methods to respond to the demands of the bu...
A finalidade do estágio curricular é a complementação do curso pretendido através da aproximação à realidade do ambiente de trabalho numa empresa, proporcionando, desta forma, a utilização prática de conteúdos adquiridos ao longo da licenciatura. O presente relatório tem por base o trabalho de 400 horas correspondente a cerca de três meses de estágio curricular na empresa de confeções Dielmar, localizada em Alc...