8 documents found, page 1 of 1
Abordagem da má evolução ponderal
Tavares, M.; Matos, I.; Bandeira, A.; Guedes, M.RESUMO Introdução: A má evolução ponderal encontra-se entre um dos motivos mais frequentes de referenciação à consulta de Pediatria. As dificuldades encontradas na definição desta entidade e as diferentes abordagens desta situação tornam difícil uma homogeneização de critérios e atitudes. Objetivo: Orientar a abordagem e seguimento das crianças com má evolução ponderal. Métodos: Revisão de artigos pertinentes p...
Alkoxylation of camphene over silica-occluded tungstophosphoric acid
Caiado, M.; Machado, A.; Santos, R. N.; Matos, I.; Fonseca, I. M.; Ramos, A. M.; Vital, J.; Valente, A. A.; Castanheiro, J. E.Silica-occluded tungstophosphoric acid (PW-S-sg) was used as an efficient, environmentally friendly heterogeneous catalyst for the liquid-phase alkoxylation of camphene into their more valuable alkyl isobornyl ether, which is used as perfume and cosmetic products, in the pharmaceutical industry, as well as in the food industry. The alkoxylation of camphene with C-1-C-4 alcohols (methanol, ethanol, 1-propanol, 2...
Psychotic aura symptoms in familial hemiplegic migraine type 2 (ATP1A2)
Barros, J.; Mendes, A.; Matos, I.; Pereira-Monteiro, J.Abstract INTRODUCTION: Neuropsychological symptoms are rare in familial hemiplegic migraine (FHM). There are no reports of psychotic symptoms in FHM type 2 (ATP1A2). We examined a family with a FHM phenotype due to a M731T mutation in ATP1A2. A 10-year follow-up allowed us to observe complex auras, including psychotic symptoms in two siblings. CASE REPORT: Male, 48 years old, with an aura that included complex ...
Effect of the sintering temperature on the properties of nanocrystalline Ca1−xS...
Lopes, M E; Melo Jorge, M. E.; Sério, S.; Nunes, M. R.; Matos, I.Nanocrystalline Ca1−xSmxMnO3 (0 ≤ x ≤ 0.4) manganites were prepared by a soft chemical method (Pechini method) followed by auto-combustion and sintering in air at 1073 or 1473 K. Single-phase powders with general composition Ca1−xSmxMnO3 were obtained after 18 h annealing. The particle and grain sizes of the substituted Sm-manganites did not exhibit variation with samarium content, but increase with increasing ...
TTC7B emerges as a novel risk factor for ischemic stroke through the convergenc...
Krug, T.; Gabriel, J.P.; Taipa, R.; Fonseca, B.V.; Domingues-Montanari, S.; Fernandez-Cadenas, I.; Manso, H.; Gouveia, L.O.; Sobral, J.; Albergaria, I.We hereby propose a novel approach to the identification of ischemic stroke (IS) susceptibility genes that involves converging data from several unbiased genetic and genomic tools. We tested the association between IS and genes differentially expressed between cases and controls, then determined which data mapped to previously reported linkage peaks and were nominally associated with stroke in published genome-...
Kalirin: a novel genetic risk factor for ischemic stroke
Krug, T.; Manso, H.; Gouveia, L.; Sobral, J.; Xavier, J.M.; Albergaria, I.; Gaspar, G.; Correia, M.; Viana-Baptista, M.; Simões, R.M.; Pinto, A.N.Cerebrovascular and cardiovascular diseases are the leading causes of death and disability worldwide. They are complex disorders resulting from the interplay of genetic and environmental factors, and may share several susceptibility genes. Several recent studies have implicated variants of the Kalirin (KALRN) gene with susceptibility to cardiovascular and metabolic phenotypes, but no studies have yet been perfo...
Mitochondrial haplogroup H1 is protective for ischemic stroke in Portuguese pat...
Rosa, A.; Fonseca, B.V.; Krug, T.; Manso, H.; Gouveia, L.; Albergaria, I.; Gaspar, G.; Correia, M.; Viana-Baptista, M.; Simões, R.M.; Pinto, A.N.The genetic contribution to stroke is well established but it has proven difficult to identify the genes and the disease-associated alleles mediating this effect, possibly because only nuclear genes have been intensely investigated so far. Mitochondrial DNA (mtDNA) has been implicated in several disorders having stroke as one of its clinical manifestations. The aim of this case-control study was to assess the c...
Prospective community-based study of stroke in Northern Portugal: incidence and...
Correia, M.; Silva, M.; Matos, I.; Magalhães, R.; Lopes, J.; Ferro, J.; Silva, M.Background and Purpose—Mortality statistics indicate that Portugal has the highest stroke mortality in Western Europe. Data on stroke incidence in Northern Portugal, the region with the highest mortality, are lacking. This study was designed to determine stroke incidence and case fatality in rural and urban populations in Northern Portugal. Methods—All suspected first-ever-in-a-lifetime strokes occurring betwee...