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Intra-articular injection of culture-expanded mesenchymal stem cells with or wi...

Bastos, Ricardo; Mathias, Marcelo; Andrade, Renato; Amaral, Ronaldo J. F. C.; Schott, Vinicius; Balduino, Alex; Bastos, Raquel; Oliveira, Joaquim M.

PURPOSE:To compare the clinical and laboratory outcomes of intra-articular injections of culture-expanded bone-derived mesenchymal stem cells (MSCs) with or without platelet-rich plasma (PRP) to intra-articular corticosteroid injections for the treatment of knee osteoarthritis (OA). METHODS:Forty-seven patients with radiographic and symptomatic knee OA were randomized into three groups for intra-articular injec...


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