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Development of multicore hybrid particles for drug delivery through the precipi...

Gonçalves, V. S. S.; Rodríguez-Rojo, S.; Matias, A. A.; Nunes, A. V. M.; Nogueira, I. D.; Nunes, D.; Fortunato, E.; Alves de Matos, A. P.; Cocero, M. J.

Hybrid lipid–polymer particles are gaining increasing interest to be applied as drug delivery systems due to their greater stability in biological fluids and enhanced cellular uptake of drugs. However, a major drawback is the fact that these particles are usually produced through techniques that use organic solvents. This work studies the possibility of producing for the first time hybrid particles composed by ...


Evaluation of cardiovascular protective effect of different apple varieties - C...

Serra, A. T.; Rocha, J.; Sepodes, B.; Matias, A. A.; Feliciano, R. P.; Carvalho, A. d.; Bronze, M. R.; Duarte, C. M. M.; Figueira, M. E.

"Epidemiological evidence supports the concept that diets rich in fruits and vegetables promote health and attenuate or delay the onset of cardiovascular disease (CVD). In particular, a reduced risk of CVD has been associated with apple consumption, probably due to the cholesterol-lowering effect of the main bioactive compounds, namely fiber and polyphenols. In this work, the effect of diet supplementation with...


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