Publisher Copyright: © 2025, European Centre for Disease Prevention and Control (ECDC). All rights reserved.; Background: Hepatitis A incidence in Portugal declined from 20.1 to 0.4/100,000 population between 1987 and 2023, changing non-vaccinated population susceptibility. This shift has contributed to more frequent out-breaks, including in 2024–25, highlighting the need to enhance surveillance and integrate s...