8 documents found, page 1 of 1
Cryptic Prophages Contribution for Campylobacter jejuni and Campylobacter coli ...
Tanoeiro, Luís; Oleastro, Mónica; Nunes, Alexandra; Marques, Andreia T.; Duarte, Sílvia Vaz; Gomes, João Paulo; Matos, António Pedro AlvesCampylobacter coli and C. jejuni, the causing agents of campylobacteriosis, are described to be undergoing introgression events, i.e., the transference of genetic material between different species, with some isolates sharing almost a quarter of its genome. The participation of phages in introgression events and consequent impact on host ecology and evolution remain elusive. Three distinct prophages, named C. j...
Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aerugin...
Morais, Diana; Tanoeiro, Luis; Marques, Andreia T.; Gonçalves, Tiago; Duarte, Aida; Matos, António Pedro Alves; Vital, Joana S.Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents resistance to several antibiotics, thus, representing a major threat to human and animal health. Phage-derived products, namely lysins, or peptidoglycan-hydrolyzing enzymes, can be an effective weapon against antibiotic-resistant bacteria. Whereas in Gram-positive bacteria, lysis from without is facilitated by the exposed peptidogly...
Cryptic Prophages Contribution for Campylobacter jejuni and Campylobacter coli ...
Tanoeiro, Luis; Oleastro, Mónica; Nunes, Alexandra; Marques, Andreia T.; Duarte, Sílvia Vaz; Gomes, João Paulo; Matos, António Pedro AlvesCampylobacter coli and C. jejuni, the causing agents of campylobacteriosis, are described to be undergoing introgression events, i.e., the transference of genetic material between different species, with some isolates sharing almost a quarter of its genome. The participation of phages in introgression events and consequent impact on host ecology and evolution remain elusive. Three distinct prophages, named C. j...
Cryptic Prophages Contribution for Campylobacter jejuni and Campylobacter coli ...
Tanoeiro, Luis; Oleastro, Mónica; Nunes, Alexandra; Marques, Andreia T.; Duarte, Sílvia Vaz; Gomes, João Paulo; Matos, António Pedro AlvesCampylobacter coli and C. jejuni, the causing agents of campylobacteriosis, are described to be undergoing introgression events, i.e., the transference of genetic material between different species, with some isolates sharing almost a quarter of its genome. The participation of phages in introgression events and consequent impact on host ecology and evolution remain elusive. Three distinct prophages, named C. j...
Cryptic prophages contribution for Campylobacter jejuni and Campylobacter coli ...
Tanoeiro, Luís; Oleastro, Mónica; Nunes, Alexandra; Marques, Andreia T.; Duarte, Sílvia Vaz; Gomes, João Paulo; Matos, António Pedro AlvesCampylobacter coli and C. jejuni, the causing agents of campylobacteriosis, are described to be undergoing introgression events, i.e., the transference of genetic material between different species, with some isolates sharing almost a quarter of its genome. The participation of phages in introgression events and consequent impact on host ecology and evolution remain elusive. Three distinct prophages, named C. j...
Liposomal delivery of newly identified prophage lysins in a Pseudomonas aerugin...
Morais, Diana; Tanoeiro, Luís; Marques, Andreia T.; Gonçalves, Tiago; Duarte, Aida; Matos, António Pedro Alves; Vital, Joana S.Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents resistance to several antibiotics, thus, representing a major threat to human and animal health. Phage-derived products, namely lysins, or peptidoglycan-hydrolyzing enzymes, can be an effective weapon against antibiotic-resistant bacteria. Whereas in Gram-positive bacteria, lysis from without is facilitated by the exposed peptidogly...
Morphologic characterization of Mycobacterium tuberculosis circulating strains ...
Silva, Carla; Alverca, Elsa; Matos, António Pedro Alves; Carvalho, Patricia A.; Portugal, Isabel; Jordão, LuísaTuberculosis (TB) is one of the major causes of mortality and morbidity worldwide accounting for 3.1 million deaths per year. This disease, caused by Mycobacterium tuberculosis (M. tuberculosis) made a deadly comeback, during the 1990’s, triggered mainly by the emergence of acquired immunodeficiency syndrome (AIDS). More recently, the emergence of multidrug resistant (MDR) and extensively drug resistant (XDR) M...
Exploring a link between mycobacteria structure and virulence
Silva, Carla; Perdigao, Joao; Alverca, Elsa; Matos, António Pedro Alves; Carvalho, Patrícia A; Portugal, Isabel; Jordão, LuísaTuberculosis (TB) is a major health problem. The emergence of multidrug resistant (MDR)Mycobacterium tuberculosis (Mtb) isolates confounds treatment strategies. In Portugal, cases of MDR-TB are reported annually with increased incidence noted in Lisbon. The majority of these MDR-TB cases are due to closely-related mycobacteria known collectively as Lisboa family and Q1 cluster. The genetic determinants linked t...