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Addressing critical fungal pathogens under a one health perspective: key insigh...

Sabino, R.; Antunes, F.; Araújo, R.; Bezerra, A. R.; Brandão, J.; Carneiro, C.; Carvalho, Agostinho; Carvalho, D.; Conceição, I. C.; Cota Medeiros, F.

Fungal infections have emerged as a significant public health concern, especially with the increasing incidence of severe mycoses caused by pathogens such as Aspergillus fumigatus, Candida auris, Candida albicans, and Cryptococcus neoformans. These fungi, listed as critical priorities by the World Health Organization, pose a heightened risk due to rising antifungal resistance and their severe impact on immunoco...


Creative Tourism: A Guide for Practitioners – How do you Regenerate Communities...

Vinagre de Castro, Tiago; Carvalho, Cláudia; Bakas, Fiona; Sancho Querol, L.; Gonçalves, Alexandra; Borges, Maria do Rosário; Albino, Sara; Matos, O.

How do you regenerate communities and places by combining culture, tourism and creativity? This booklet is intended to provide clarification and guidance to practitioners in the cultural, creative and tourism sectors currently developing or wishing to develop creative tourism projects based on collaborative practices, particularly in rural areas and small cities.


Towards a global perspective of environmental health: defining the research gro...

Virgolino, A.; Antunes, F.; Santos, O.; Costa, A.; De Matos, M. G.; Bárbara, C.; Bicho, M.; Caneiras, C.; Sabino, R.; Núncio, M. S.; Matos, O.

Environmental health is at the intersection between health and the environment. However, it still has a recent (and narrow) history as a scientific area, mainly addressing human biomonitoring and toxicological issues. Only recently additional environmental ‘layers’, other than the traditional chemical, biological and physical environmental determinants, have been considered. This broader perspective of environm...

Date: 2020   |   Origin: Repositório ISCTE

Towards a Global Perspective of Environmental Health: Defining the Research Grou...

Virgolino, A.; Antunes, F.; Santos, O.; Costa, A.; Gaspar de Matos, M.; Bárbara, C.; Bicho, M.; Caneiras, C.; Sabino, Raquel; Núncio, Sofia; Matos, O.

Environmental health is at the intersection between health and the environment. However, it still has a recent (and narrow) history as a scientific area, mainly addressing human biomonitoring and toxicological issues. Only recently additional environmental ‘layers’, other than the traditional chemical, biological and physical environmental determinants, have been considered. This broader perspective of environme...


Multicentre study highlighting clinical relevance of new high-throughput method...

Esteves, F.; Sousa, B. de; Calderón, E. J.; Huang, L.; Badura, R.; Maltez, F.; Bassat, Q.; de Armas, Y.; Antunes, F.; Matos, O.

Pneumocystis jirovecii causes severe interstitial pneumonia (PcP) in immunosuppressed patients. This multicentre study assessed the distribution frequencies of epidemiologically relevant genetic markers of P. jirovecii in different geographic populations from Portugal, the USA, Spain, Cuba and Mozambique, and the relationship between the molecular data and the geographical and clinical information, based on a m...


Portugal and Angola: similarities and differences in Toxoplasma gondii seroprev...

LOBO, M. L.; PATROCINIO, G.; Sevivas, T.; Sousa, B. de; Matos, O.

In this study we determined the presence of IgM/IgG antibodies to Toxoplasma gondii in sera of 155 and 300 pregnant women from Lisbon (Portugal) and Luanda (Angola), respectively, and evaluated the potential risk factors associated with this infection. DNA detection was performed by PCR assays targeting T. gondii regions (RE/B1). Overall, 21·9% (10·9% IgG, 10·9% IgG/IgM) of the Lisbon women and 27·3% (23·7%, Ig...


Diagnosis of Pneumocystis pneumonia: evaluation of four serologic biomarkers

Esteves, F.; Calé, S. S.; Badura, Robert; de Boer, M.G.; Maltez, F.; Calderón, E. J.; van der Reijden, T. J.; Márquez-Martín, E.; Antunes, Francisco

The diagnosis of Pneumocystis pneumonia (PCP) relies on microscopic visualization of Pneumocystis jirovecii organisms or DNA detection in pulmonary specimens. This study aimed to assess the usefulness of (1-3)-β-d-glucan (BG), Krebs von den Lungen-6 antigen (KL-6), lactate dehydrogenase (LDH) and S-adenosyl methionine (SAM) as serologic biomarkers in the diagnosis of PCP. Serum levels of BG, KL-6, LDH and SAM w...


Watering and mineral supply effects on plant production, on hydrosoluble metabo...

Matos, O.; Baptista, S.; Passarinho, J.A.; Delgado, F.M.G.; Ricardo, C. Pinto; Vilas-Boas, L.

Calamintha bactica, Origonum vulgaris and Cuminum cyminum have been studied for their capacities as a source of antifungal compounds. One set of these plants grown under water stress. The other set of plants was submitted to different mineral nutrition. The plant material obtained after grinding, were extracted with MeOH or EtOAc, fractionated with organic solvents, and tested for their antifungal properties. C...


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