Background/objectives: Chronic lymphocytic leukemia (CLL) exhibits a heterogeneous clinical course influenced by genetic factors, such as the mutational status of immunoglobulin variable regions (IGHV). Recently, B-cell receptor (BcR) stereotypes have shown promising prognostic value, potentially surpassing IGHV status. The PAIS study analyzed BcR stereotypes and IGHV mutations in newly diagnosed Portuguese CLL...
ABSTRACT: Facilitating the exploration of adolescents’ questions regarding nature is vital. Research suggests that their questions are important as they can reveal their interests in particular subjects and further guide their learning process. We designed a quasi-experimental study for 68 adolescents in an outdoor and indoor setting to assess the efficacy of the audio-learning materials in promoting their inte...
The growing interest in innovative pedagogies within education for sustainable development (ESD) calls for a renewed set of pedagogical practices. In responding to this challenge, this article draws on backcasting, a future studies method, to support education for ESD competencies among youths. It presents the design, trial, and results of one intervention designed to test the method in the context of secondary...
O presente relatório realizou-se em contexto do Mestrado de Educação Pré-Escolar e Ensino do 1.º Ciclo do Ensino Básico, para a obtenção de grau de Mestre. O mesmo apresenta uma reflexão das aprendizagens mais significativas, resultantes da experiência de estágio no ano letivo de 2021/2022, nos contextos de Educação Pré-escolar e de 1.º Ciclo do Ensino Básico. O desenvolvimento do presente estudo teve como prin...
Direct contact with nature is paramount in deepening children’s and teenagers’ interest in biodiversity. Learning materials chosen to convey information and engage participants during outings in nature-rich environments are varied and can support rich learning experiences. For this purpose, learning materials can be acquired "off-the-shelf" or developed for site-specific locations or projects. However, there is...
Num contexto escolar em que os alunos estão menos vezes do que o desejável em contacto direto com ambientes naturais, pretende-se, no âmbito do projeto de investigação Guia de Campo, disponibilizar a professores, pais e jovens um conjunto de atividades de exploração da natureza idealizadas de modo a diversificar os tipos de inteligência, de experiências e de elementos naturais abrangidos. De acordo com a aborda...
Questioning can be an important instrument to promote students' interest in nature. In this study, based on questions from local adolescents about nature, we designed mobile learning materials focused on local nature-rich environments in the form of podcast episodes and tested them, in a quasi-experimental design, with a new group of adolescents to assess their efficacy in promoting participants’ curiosity abou...
In Portugal, the genetic diversity, origin of HBV and the Portuguese role in the dissemination of HBV worldwide were never investigated. In this work, we studied the epidemic history and transmission dynamics of HBV genotypes that are endemic in Portugal. HBV pol gene was sequenced from 130 patients followed in Lisbon. HBV genotype A was the most prevalent (n = 54, 41.5%), followed by D (n = 44, 33.8%), and E (...
In Portugal, the genetic diversity, origin of HBV and the Portuguese role in the dissemination of HBV worldwide were never investigated. In this work, we studied the epidemic history and transmission dynamics of HBV genotypes that are endemic in Portugal. HBV pol gene was sequenced from 130 patients followed in Lisbon. HBV genotype A was the most prevalent (n = 54, 41.5%), followed by D (n = 44, 33.8%), and E (...
Here we present Field Guide, a mobile application (app) designed to connect communities to nature-rich environments, which play a crucial role in nature conservation efforts. The app aligns to a mode of science communication that seeks to establish direct contact between publics and specialised scientific communities, most commonly known as the ’ask a scientist’ approach. Field Guide uses a geolocation position...