4 documents found, page 1 of 1
HIV-2 infection is associated with preserved GALT homeostasis and epithelial in...
Fernandes, S; Pires, A; Matoso, P; Ferreira, C; Nunes-Cabaço, H; Correia, L; Valadas, E; Poças, J; Pacheco, P, et al.The mechanisms that enable preservation of gut mucosal integrity during persistent viral replication and inherent inflammation remain unclear. Here, we investigated, for the first time, gut homeostasis in HIV-2 infection, a naturally occurring form of attenuated HIV disease. We found viral replication in both sigmoid and ileum of asymptomatic HIV-2+ patients (range: 240-851 circulating CD4+T-cells per μl) despi...
Coreceptor Usage by HIV-1 and HIV-2 Primary Isolates: The Relevance of CCR8 Che...
Calado, M; Matoso, P; Santos-Costa, Q; Espirito-Santo, M; Machado, J; Rosado, L; Antunes, K; Mansinho, K; Lopes, MM; Maltez, F; Santos-Ferreira, MOThe human immunodeficiency virus replication cycle begins by sequential interactions between viral envelope glycoproteins with CD4 molecule and a member of the seven-transmembrane, G-protein-coupled, receptors' family (coreceptor). In this report we focused on the contribution of CCR8 as alternative coreceptor for HIV-1 and HIV-2 isolates. We found that this coreceptor was efficiently used not only by HIV-2 but...
Estudo fenotípico de estirpes HIV-2 isoladas de indivíduos em diferentes fases ...
Matoso, P; Lobão, Daniela; Costa, Quirina Santos; Pereira, José Moniz; Pereira, JMAzevedo
Characterization of coreceptor usage by HIV-2 strains obtained from patients in...
Matoso, P; Lobão, D; Costa, QSantos; Pereira, JMoniz; Pereira, JMAzevedo