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Early Experience in Extraperitoneal Robotic Assisted Radical Prostatectomy with...

Marques Monteiro, Miguel; Teixeira, David; Nunes-Carneiro, Diogo; Cabral, João; Teves, Frederico; Soares, José; Fraga, Avelino

Introduction:The Hugo™ RAS system represents a novel robotic platform recently implemented in our department. Despite its introduction, there is still a scarcity of data regarding extraperitoneal robot-assisted radical prostatectomy (eRARP) carried out using this system. Our primary aim is to compare perioperative, early functional, and oncological outcomes of eRARP with the Hugo RAS System during our centre’s ...

Data: 2025   |   Origem: Acta Urológica Portuguesa

Scoping Review on Management of Nephrostomy – and Double J-Stent – Associated I...

Oliveira, Beatriz; Magalhães, Marta; Vinagre, Nuno; Teves, Frederico; Fraga, Avelino

Catheter-associated urinary tract infections (CA-UTIs) refer to infections related to indwelling urinary catheters and are the main cause of hospital-acquired urinary tract infections. Most literature, including the European Urological Association (EAU) Urological Infections Guidelines, defines CA-UTIs as infections specifically associated with urethral catheters, excluding catheter-associated infections relate...

Data: 2025   |   Origem: Acta Urológica Portuguesa

Robot-Assisted Partial Nephrectomy for Totally Endophytic Renal Tumor

Mesquita, Sofia; Sousa, Diogo; Fraga, Avelino; Silva-Ramos, Miguel

.; .

Data: 2025   |   Origem: Acta Urológica Portuguesa

The Role of Liquid Biopsy in Metastatic Prostate Cancer

Glória, Joana; Nunes-Carneiro, Diogo; Fraga, Avelino

Prostate cancer is the second most common malignancy in men. The high prevalence of prostate cancer, as well as its relatively indolent clinical course and the emerging therapeutic options, have led to the need to identify biomarkers that may aid in clinical decisions and may reflect response to treatments. “Liquid biopsy” is a generic term applied to the study of biomarkers attributed to tumors that are circul...

Data: 2020   |   Origem: Acta Urológica Portuguesa

Remaining kidney volume indexed to weight as a strong predictor of estimated gl...

Nunes-Carneiro, Diogo; Madanelo, Mariana; Silva, Filipa; Pestana, Nicole; Ribeiro, Catarina; Gil‐Sousa, Diogo; Martins, La Salete; Almeida, Manuela

The donors' estimated glomerular filtration rate (eGFR) after living nephrectomy has been a concern, particularly in donors with smaller kindeys. Therefore, we developed this retrospective observational study in 195 donors to determine the ability remaining kidney volume indexed to weight (RKV/W) to predict eGFR at 1 year through multivariate linear regression and to explore this relationship between annual eGF...


The impact of the coronavirus disease 2019 pandemic on the utilisation of emerg...

Madanelo, Mariana; Ferreira, Carlos; Nunes-Carneiro, Diogo; Pinto, André; Rocha, Maria Alexandra; Correia, Jorge; Teixeira, Bernardo; Mendes, Gonçalo

Objectives: To compare the number of patients attending the Urology Emergency Department (ED) of the Centro Hospitalar Universitário do Porto (CHUP), as well as their demographic characteristics, the reasons for admission, the clinical severity under the Manchester triage system (MTS), and the need for emergency surgery or hospitalisation, during the coronavirus disease 2019 (COVID-19) pandemic and the equivale...


Urinary Biomarkers in Bladder Cancer: Where Do We Stand and Potential Role of E...

Castanheira De Oliveira, Manuel; Caires, Hugo R.; Oliveira, Maria J; Fraga, Avelino; Vasconcelos, M. Helena; Ribeiro, Ricardo

Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and proteins constantly transferred between different cell types, contributing to autocrine and paracrine signaling. In recent years, they have been shown to play vital roles, not only in normal biological functions, but also in pathol...


Urinary biomarkers in bladder cancer : where do we stand and potential role of ...

Oliveira, Manuel Castanheira de; Caires, Hugo R.; Oliveira, Maria J.; Fraga, Avelino; Vasconcelos, M. Helena; Ribeiro, Ricardo

Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and proteins constantly transferred between different cell types, contributing to autocrine and paracrine signaling. In recent years, they have been shown to play vital roles, not only in normal biological functions, but also in pathol...


EXCISION OF A TUMORAL THROMBUS FROM THE INFERIOR VENA CAVA

Mendes, Daniel; Machado, Rui; Ramos, Miguel; Fraga, Avelino; de Almeida, Rui

Relatamos um caso clínico de um doente submetido a recessão cirurgica de tromobo tumoral da veia cava inferior e posterior recontrução vascular.

Data: 2019   |   Origem: Angiologia e Cirurgia Vascular

Epigenome-wide DNA methylation profiling of periprostatic adipose tissue in pro...

Cheng, Yan; Monteiro, Cátia; Matos, Andreia; You, Jiaying; Fraga, Avelino; Pereira, Carina; Catalán, Victoria; Rodríguez, Amaia; Gómez-Ambrosi, Javier

Background: Periprostatic adipose tissue (PPAT) has been recognized to associate with prostate cancer (PCa) aggressiveness and progression. Here, we sought to investigate whether excess adiposity modulates the methylome of PPAT in PCa patients. DNA methylation profiling was performed in PPAT from obese/overweight (OB/OW, BMI > 25 kg m−2) and normal weight (NW, BMI < 25 kg m−2) PCa patients. Significant differen...


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