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Identification of 170 new long noncoding RNAs in Schistosoma mansoni.

Oliveira, Victor Fernandes de; Moraes, Lauro Ângelo Gonçalves de; Mota, Ester Alves; Passos, Liana Konovaloff Jannotti; Coelho, Paulo Marcos Zech

Long noncoding RNAs (lncRNAs) are transcripts generally longer than 200 nucleotides with no or poor protein coding potential, and most of their functions are also poorly characterized. Recently, an increasing number of studies have shown that lncRNAs can be involved in various critical biological processes such as organism development or cancer progression. Little, however, is known about their effects in helmi...

Date: 2019   |   Origin: Oasisbr

Characterisation of major vault protein during the life cycle of the human para...

Reis, Eneida Virgínia; Pereira, Roberta Verciano; Gomes, Matheus de Souza; Passos, Liana Konovaloff Jannotti; Babá, Élio Hideo

Vaults are ribonucleoproteins (13MDa) highly conserved among lower and higher eukaryotes. Their association produces a complex composed of three proteins named Major Vault Protein (MVP), vault (PolyADP-ribose) polymerase (VPARP) and Telomerase-associated protein (TEP1), plus a small untranslated RNA. The exact function of this complex is unknown, although the biological role of vaults has been associated with m...

Date: 2015   |   Origin: Oasisbr

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