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Leishmaniasis: scientific advances in control, diagnosis and molecular epidemio...

Maurício, Isabel

Leishmaniases are neglected tropical diseases caused by protozoan parasites of the genus Leishmania. Although control strategies and efforts have contributed to a reduction in the overall prevalence and in the burden of disease, up to 1 million cases still occur every year, and visceral leishmaniasis still kills up to 90 000 people annually. Selected advances in the control of Leishmaniasis are presented and di...


Improved dsRNA isolation and purification method validated by viral dsRNA detec...

Cardoso, Fernando M.H.; Elias, Alexandre; Pereira, Inês; Maurício, Isabel; Matos, Olga

Accurate genomic sequencing demands high-quality double-stranded RNA (dsRNA). Existing methods for dsRNA extraction from yeast, fungi, and plants primarily rely on cellulose, suitable only for small volume extractions, or the time-consuming lithium chloride precipitation. To streamline the traditional phenol-chloroform-based dsRNA extraction method, the main challenge is the reduction of mitochondrial DNA (mtDN...


PRINCIPAIS HELMINTOSES NEGLIGENCIADAS – ONTEM, HOJE E AMANHÃ NO IHMT

Afonso, Ana; Calado, Maria; Maurício, Isabel; Belo, Silvana

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Identificação de um novo haplótipo de fasciola hepatica

Roque, Cláudio André Martins; Beato, Sílvia; Maurício, Isabel; Belo, Silvana

F. hepatica é o agente etiológico da Fasciolose humana/animal, e tem a capacidade de parasitar diversas espécies animais, principalmente herbívoros e omnívoros (ovinos, bovinos, caprinos, etc.) onde pode ser encontrado no fígado e canais biliares, tendo também a capacidade, de acidentalmente infetar o Homem. Este parasita apresenta uma distribuição cosmopolita sendo mais frequente em regiões pantanosas sujeitas...


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