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Diagnostic testing for chronic spontaneous urticaria with or without angioedema

Bernstein, Jonathan A.; Ansotegui, Ignacio; Asero, Riccardo; Banerji, Aleena; Betschel, Stephen; Craig, Timothy; García-Abujeta, José Luis

Publisher Copyright: © 2025 The Authors; Chronic spontaneous urticaria (CSU), with or without angioedema, is heterogeneous and comprised of different endotypes and phenotypes. Because acute urticaria will mostly resolve spontaneously, routine testing and laboratory evaluation is not required unless supported by the clinical history or physical examination. With the advent of omalizumab, there has been a surge o...


Concepts for the Development of Person-Centered, Digitally Enabled, Artificial ...

Bousquet, Jean; Schünemann, Holger J.; Sousa-Pinto, Bernardo; Zuberbier, Torsten; Togias, Alkis; Samolinski, Boleslaw; Bedbrook, Anna

Funding Information: This work has received funding from ARIA (Allergic Rhinitis and its Impact of Asthma); CATALYSE (Climate Action To Advance HeaLthY Societies in Europe), the European Union\u2019s Horizon Europe research and innovation program under grant agreement no. 101057131; FRAUNHOFER Institute for Translational Medicine and Pharmacology (ITMP), Immunology and Allergology, Berlin, Germany; University o...


Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity

Bousquet, Jean; Anto, Josep M.; Sousa-Pinto, Bernardo; Czarlewski, Wienczyslawa; Bedbrook, Anna; Haahtela, Tari; Klimek, Ludger; Pfaar, Oliver

Funding Information: The authors thank Ms Véronique Pretschner for submitting the paper. MASK‐air has been supported by Charité Universitätsmedizin Berlin, EU grants (EU Structural and Development Funds Languedoc Roussillon and Region PACA; POLLAR: EIT Health; Twinning: EIP on AHA; Twinning DHE: H2020; Catalyse: Horizon Europe) and educational grants from Mylan‐Viatris, ALK, GSK, Novartis, Stallergènes‐Greer an...


Why a complete response is the treatment aim in chronic spontaneous urticaria

Bernstein, Jonathan A.; Giménez-Arnau, Ana; Maurer, Marcus; Staubach, Petra; Barbier, Nathalie; Hua, Eva; Severin, Thomas; Laires, Pedro A.

Funding Information: The authors thank Bharat Suryawanshi of IQVIA India Ltd. and Sandip Acharya of Novartis Hyderabad Pvt Ltd. for their statistical analyses support, as well as Gillian Brodie, MSc and Linda Hassanali, PhD of Novartis Ireland Ltd. and Mohammad Fahad Haroon, PhD of Novartis Hyderabad Pvt. Ltd. for their medical writing and editorial support, which was funded by Novartis Pharma AG, Basel, Switze...


Bruton's tyrosine kinase inhibition—An emerging therapeutic strategy in immune-...

Mendes-Bastos, Pedro; Brasileiro, Ana; Kolkhir, Pavel; Frischbutter, Stefan; Scheffel, Jörg; Moñino-Romero, Sherezade; Maurer, Marcus

Funding Information: PM‐B received honoraria for acting as a consultant and/or as a speaker for AbbVie, Janssen, Novartis, LEO Pharma, Almirall, Sanofi, Viatris, L’Oréal, and Cantabria Labs and served as a principal investigator in clinical trials supported by AbbVie, Sanofi, and Novartis. AB received honoraria for lectures and educational events for LEO Pharma, Janssen‐Cilag, AbbVie, and Novartis. PK received ...


ARIA digital anamorphosis

Bousquet, Jean; Anto, Josep M.; Bachert, Claus; Haahtela, Tari; Zuberbier, Torsten; Czarlewski, Wienczyslawa; Bedbrook, Anna; Bosnic-Anticevich, Sinthia

Funding: MA reports personal fees from POCI-01-0145-FEDER-029130 mINSPIRERS—mHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases—generalization and evaluation of gamification, peer support and advanced image processing technologies from ERDF (European Regional Development Fund) funded by the COMPETE2020 and by National Funds through FCT (Fundação para a Ciência e a ...


Author Correction

Lozza, Laura; Moura-Alves, Pedro; Domaszewska, Teresa; Crespo, Carolina Lage; Streata, Ioana; Kreuchwig, Annika; Puyskens, Andreas; Bechtle, Marina

Publisher Copyright: © 2020, The Author(s).; An amendment to this paper has been published and can be accessed via a link at the top of the paper.


The Henna pigment Lawsone activates the Aryl Hydrocarbon Receptor and impacts s...

Lozza, Laura; Moura-Alves, Pedro; Domaszewska, Teresa; Lage Crespo, Carolina; Streata, Ioana; Kreuchwig, Annika; Puyskens, Andreas; Bechtle, Marina

As a first host barrier, the skin is constantly exposed to environmental insults that perturb its integrity. Tight regulation of skin homeostasis is largely controlled by the aryl hydrocarbon receptor (AhR). Here, we demonstrate that Henna and its major pigment, the naphthoquinone Lawsone activate AhR, both in vitro and in vivo. In human keratinocytes and epidermis equivalents, Lawsone exposure enhances the pro...


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