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Aspirin but not statins is inversely related to gastric cancer with a duration–...
Pastorino, R; Pires Marafon, D; Sassano, M; Hoxhaj, I; Pelucchi, C; Liao, LM; Rabkin, CS; Sinha, R; Lunet, N; Morais, S; Zaridze, D; Maximovich, DBackground: Aspirin and statins have been suggested to have potential chemopreventive effects against gastric cancer (GC), although the results of previous studies have been inconsistent. This study therefore aimed to investigate the association between the use of aspirin and statins and GC. Methods: A pooled analysis of seven case-control studies within the Stomach Cancer Pooling Project, including 3220 cases ...
Dietary intake of vitamin C and gastric cancer: a pooled analysis within the St...
Sassano, M; Seyyedsalehi, MS; Collatuzzo, G; Pelucchi, C; Bonzi, R; Ferraroni, M; Palli, D; Yu, G-P; Zhang, Z-F; López-Carrillo, L; Lunet, N; Morais, SBackground: Previous studies suggest that dietary vitamin C is inversely associated with gastric cancer (GC), but most of them did not consider intake of fruit and vegetables. Thus, we aimed to evaluate this association within the Stomach cancer Pooling (StoP) Project, a consortium of epidemiological studies on GC. Methods: Fourteen case–control studies were included in the analysis (5362 cases, 11,497 controls...
Mushroom consumption and risk of gastric cancer: a pooled analysis within the s...
Ba, DM; Ssentongo, P; Pelucchi, C; Negri, E; Palli, D; Ferraroni, M; Zhang, ZF; Yu, GP; Tsugane, S; Hidaka, A; Hamada, GS; Zaridze, D; Maximovich, DEdible mushrooms have high concentrations of vitamins and minerals. They are considered ‘functional foods’ for their disease-prevention properties. Mushroom consumption may reduce the risk of gastric cancer, the fifth most common cancer worldwide. We investigated the association between mushroom consumption and gastric cancer risk in a pooled analysis within the Stomach Cancer Pooling (StoP) Project and in a me...
The mediating role of combined lifestyle factors on the relationship between ed...
Alicandro, G; Bertuccio, P; Collatuzzo, G; Pelucchi, C; Bonzi, R; Liao, LM; Rabkin, CS; Sinha, R; Negri, E; Dalmartello, M; Zaridze, D; Maximovich, DBackground: The causal pathway between high education and reduced risk of gastric cancer (GC) has not been explained. The study aimed at evaluating the mediating role of lifestyle factors on the relationship between education and GC Methods: Ten studies with complete data on education and five lifestyle factors (smoking, alcohol drinking, fruit and vegetable intake, processed meat intake and salt consumption) w...
Identifying the Profile of Helicobacter pylori-Negative Gastric Cancers: A Case...
Morais, S; Peleteiro, B; Araújo, N; Malekzadeh, R; Ye, W; Plymoth, A; Tsugane, S; Hidaka, A; Hamada, GS; López-Carrillo, L; Zaridze, D; Maximovich, DBackground: The prevalence of Helicobacter pylori-negative gastric cancer (HpNGC) can be as low as 1%, when infection is assessed using more sensitive tests or considering the presence of gastric atrophy. HpNGC may share a high-risk profile contributing to the occurrence of cancer in the absence of infection. We estimated the proportion of HpNGC, using different criteria to define infection status, and compared...
Family History and Gastric Cancer Risk: A Pooled Investigation in the Stomach C...
Vitelli-Storelli, F; Rubín-García, M; Pelucchi, C; Benavente, Y; Bonzi, R; Rota, M; Palli, D; Ferraroni, M; Lunet, N; Morais, S; Ye, W; Plymoth, AAlthough there is a clear relationship between family history (FH) and the risk of gastric cancer (GC), quantification is still needed in relation to different histological types and anatomical sites, and in strata of covariates. The objective was to analyze the risk of GC according to first-degree FH in a uniquely large epidemiological consortium of GC. This investigation includes 5946 cases and 12,776 control...
Fruits and vegetables intake and gastric cancer risk: A pooled analysis within ...
Ferro, A; Costa, AR; Morais, S; Bertuccio, P; Rota, M; Pelucchi, C; Hu, J; Johnson, KC; Zhang, ZF; Palli, D; Ferraroni, M; Yu, GP; Bonzi, RA low intake of fruits and vegetables is a risk factor for gastric cancer, although there is uncertainty regarding the magnitude of the associations. In our study, the relationship between fruits and vegetables intake and gastric cancer was assessed, complementing a previous work on the association betweenconsumption of citrus fruits and gastric cancer. Data from 25 studies (8456 cases and 21 133 controls) with...
Polyphenol Intake and Gastric Cancer Risk: Findings from the Stomach Cancer Poo...
Vitelli-Storelli, F; Rossi, M; Pelucchi, C; Rota, M; Palli, D; Ferraroni, M; Lunet, N; Morais, S; López-Carrillo, L; Zaridze, DG; Maximovich, DPhenolic compounds may exert a favorable effect on the risk of several cancer types, including gastric cancer (GC). However, selected polyphenol classes have not been adequately investigated in relation to GC. The aim of this study is to evaluate the association between the intake of polyphenols in relation to GC risk. We used data from the Stomach cancer Pooling (StoP) Project, including 10 studies from six co...