3 documents found, page 1 of 1
The Portuguese Society of Rheumatology position paper on the use of biosimilars
Fonseca, JE; Gonçalves, J; Araújo, F; Cordeiro, I; Teixeira, F; Canhão, H; Pereira da Silva, JA; Garcês, S; Miranda, LC; Ramiro, Sofia; Roxo, AnaBiotechnological drugs have become a fundamental resource for the treatment of rheumatic patients. Patent expiry of some of these drugs created the opportunity for biopharmaceutical manufacturers to develop biosimilar drugs intended to be as efficacious as the originator product but with a lower cost to healthcare systems. Due to the complex manufacturing process and highly intricate structure of biologicals, a...
Osteoarthritis medical labelling and health-related quality of life in the gene...
Lourenço, S; Lucas, R; Araújo, F; Bogas, M; Santos, RA; Barros, HBackground: Osteoarthritis is the most common chronic joint disease. In the absence of an effective medical treatment and due to the chronic nature of this condition, an osteoarthritis medical diagnosis may finally result in decreased health-related quality of life. Therefore, the aim of this study was to measure the impact of the osteoarthritis medical labelling on physical and mental health-related quality of...
Recomendações Portuguesas para utilização de Metotrexato no tratamento de doenç...
Canhão, H; Santos, MJ; Costa, L; Bogas, M; Mourão, AF; Machado, P; Fonseca, JE; Pereira da Silva, JAOBJECTIVES: To develop Portuguese evidence-based recommendations for the use of methotrexate (MTX) in daily clinical practice in rheumatic disorders. METHODS: The Portuguese project was integrated in the multinational 3E Initiative (Evidence, Expertise, Exchange) 2007-2008 where a total of 751 rheumatologists from 17 countries have participated. Ten clinical questions concerning the use of MTX in rheumatic dise...