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Real-world effectiveness of aromatase inhibitors and fulvestrant in HR+/HER2- a...

Teodoro, Maria Inês; Mayer, Alexandra; da Costa Miranda, Ana; Nunes, Hugo; da Costa, Filipa Alves; Lourenço, António

© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.; BACKGROUND: Monotherapy with aromatase inhibitors and fulvestrant were the standard-of-care for hormone receptor-positive (HR+)/human epidermal growth factor receptor-type2 negative (HER2-) advanced breast cancer, before integration of cyclin-dependent kinase 4/6 inhibitors. Effectiveness data is essential for regulatory ...


The effect of timeliness of care on lung cancer survival

Guerreiro, Teresa; Mayer, Alexandra; Aguiar, Pedro; Araújo, António; Nunes, Carla

Publisher Copyright: © 2023 The Author(s).; Background: Timeliness of care is an important dimension of healthcare quality but it’s unclear whether it improves clinical outcomes in lung cancer (LC) patients. Objectives: This study aims to analyze treatment patterns, time-to-treatment (TTT) and the impact of treatment timeliness (TT) in overall survival (OS) of patients diagnosed with LC in 2009–2014 in a popula...


Effectiveness of palbociclib with aromatase inhibitors for the treatment of adv...

Alves da Costa, Filipa; Cardoso Borges, Fábio; Ramos, Adriana; Mayer, Alexandra; Brito, Claudia; Ramos, Catarina; Bernardo, Catarina; Cossito, Mariane

Funding Information: The authors acknowledge the RON network that cooperated in providing up-to-date information on cases diagnosed and treated with the drug of interest. Participating institutions: Centro Hospitalar Universitário de São João, Centro Hospitalar Universitário Lisboa Norte, Centro Hospitalar Universitário do Algarve, Hospital de Braga, Centro Hospitalar e Universitário de Coimbra, Centro Hospital...


Lung cancer

Guerreiro, Teresa; Antunes, Luis; Bastos, Joana; Mayer, Alexandra; Forjaz, Goncalo; Araujo, AntÓnio; Nunes, Carla

BACKGROUND/AIM: This study characterized lung cancer (LC) in Portugal, to capture sex differences, regional variation, and spatial distribution. PATIENTS AND METHODS: Variables: age, sex, vital status, region of residence, degree of urbanization, histologic types and stage at diagnosis. Spatial analyses conducted to identify high (HIC) and low incidence (LIC) clusters. RESULTS: In total, 11,642 cases were diagn...


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